Apolipoproteins A-I, B, and C-III and Obesity in Young Adult Cherokee
Joint Authors
Blackett, Piers
Wang, Wenyu
Khan, Sohail
Lee, Elisa
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Since young adult Cherokee are at increased risk for both diabetes and cardiovascular disease, we assessed association of apolipoproteins (A-I, B, and C-III in non-HDL and HDL) with obesity and related risk factors.
Obese participants (BMI ≥ 30) aged 20–40 years (n=476) were studied.
Metabolically healthy obese (MHO) individuals were defined as not having any of four components of the ATP-III metabolic syndrome after exclusion of waist circumference, and obese participants not being MHO were defined as metabolically abnormal obese (MAO).
Associations were evaluated by correlation and regression modeling.
Obesity measures, blood pressure, insulin resistance, lipids, and apolipoproteins were significantly different between groups except for total cholesterol, LDL-C, and HDL-apoC-III.
Apolipoproteins were not correlated with obesity measures with the exception of apoA-I with waist and the waist : height ratio.
In a logistic regression model apoA-I and the apoB : apoA-I ratio were significantly selected for identifying those being MHO, and the result (C-statistic = 0.902) indicated that apoA-I and the apoB : apoA-I ratio can be used to identify a subgroup of obese individuals with a significantly less atherogenic lipid and apolipoprotein profile, particularly in obese Cherokee men in whom MHO is more likely.
American Psychological Association (APA)
Wang, Wenyu& Blackett, Piers& Khan, Sohail& Lee, Elisa. 2017. Apolipoproteins A-I, B, and C-III and Obesity in Young Adult Cherokee. Journal of Lipids،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1182317
Modern Language Association (MLA)
Wang, Wenyu…[et al.]. Apolipoproteins A-I, B, and C-III and Obesity in Young Adult Cherokee. Journal of Lipids No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1182317
American Medical Association (AMA)
Wang, Wenyu& Blackett, Piers& Khan, Sohail& Lee, Elisa. Apolipoproteins A-I, B, and C-III and Obesity in Young Adult Cherokee. Journal of Lipids. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1182317
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1182317