Development of a RP-HPLC Method for Separating and Quantifying Muscimol in Different Developmental Stages of the Fungus Amanita muscaria

Joint Authors

Ávila, Emersón León
Guevara-Pulido, James

Source

Journal of Chemistry

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-11-20

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Chemistry

Abstract EN

A simple RP-HPLC method was designed for the quantification of muscimol (5-(aminomethyl)-isoxazol-3-ol) present in five aqueous extracts of Amanita muscaria each from a different developmental stage.

Results show that the maximum concentration of muscimol (1,210 mg/ml) was found in the young mushroom stage of development.

Moreover, it was also found that this concentration progressively decreases as the fungus ages.

The developed method is a simple but effective method for the quantification of muscimol, a widely important metabolite for the pharmaceutical industry as a possible treatment for tardive dyskinesia and Parkinson’s disease.

American Psychological Association (APA)

Ávila, Emersón León& Guevara-Pulido, James. 2020. Development of a RP-HPLC Method for Separating and Quantifying Muscimol in Different Developmental Stages of the Fungus Amanita muscaria. Journal of Chemistry،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1182449

Modern Language Association (MLA)

Ávila, Emersón León& Guevara-Pulido, James. Development of a RP-HPLC Method for Separating and Quantifying Muscimol in Different Developmental Stages of the Fungus Amanita muscaria. Journal of Chemistry No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1182449

American Medical Association (AMA)

Ávila, Emersón León& Guevara-Pulido, James. Development of a RP-HPLC Method for Separating and Quantifying Muscimol in Different Developmental Stages of the Fungus Amanita muscaria. Journal of Chemistry. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1182449

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1182449