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Graphene Oxide as a Nanocarrier for Controlled Loading and Targeted Delivery of Typhonium giganteum Drugs
Joint Authors
Gu, Xiaohua
Cao, Rui
Li, Fu
Li, Yan
Jia, Hongge
Yu, Hui
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
In this study, Typhonium giganteum containing dual-function nanofibers composed of poly(butylene carbonate), polylactic acid, and graphene oxide (PBC/PLA/GO) were successfully fabricated by electrospinning.
The results from thermogravimetric analysis (TG), differential scanning calorimetry (DSC), and Fourier-transform infrared spectroscopy (FTIR) indicate that no interactions occurred between PBC and PLA.
The nanofiber microstructure upon which graphene oxide was evenly distributed was studied by scanning electron microscopy (SEM) and showed good silk properties.
The nanofibers can be used as a drug carrier since loaded Typhonium giganteum fibers possess excellent biocompatibility.
Such nanofibers are effective in inhibiting the proliferation of A549 lung cancer cells, and thus they have potential for replacing chemotherapy-based treatments of lung cancer.
In addition, the PBC/PLA/GO nanofibers degrade in physiological and natural environments, which is an important feature when engineering tissues and environment-friendly materials.
American Psychological Association (APA)
Gu, Xiaohua& Cao, Rui& Li, Fu& Li, Yan& Jia, Hongge& Yu, Hui. 2018. Graphene Oxide as a Nanocarrier for Controlled Loading and Targeted Delivery of Typhonium giganteum Drugs. Journal of Chemistry،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1182503
Modern Language Association (MLA)
Gu, Xiaohua…[et al.]. Graphene Oxide as a Nanocarrier for Controlled Loading and Targeted Delivery of Typhonium giganteum Drugs. Journal of Chemistry No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1182503
American Medical Association (AMA)
Gu, Xiaohua& Cao, Rui& Li, Fu& Li, Yan& Jia, Hongge& Yu, Hui. Graphene Oxide as a Nanocarrier for Controlled Loading and Targeted Delivery of Typhonium giganteum Drugs. Journal of Chemistry. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1182503
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1182503