Solvent-Free Ring Cleavage Hydrazinolysis of Certain Biginelli Pyrimidines
Joint Authors
Ghabbour, Hazem A.
Eldehna, Wagdy M.
Said, Mohamed A.
Kabil, Maha M.
Al-shakliah, Nasser S.
Abdel-Aziz, Hatem A.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Certain Biginelli pyrimidines with ester substitution in C5 were subjected to unexpected ring opening upon solvent-free reaction with hydrazine hydrate to give three products: pyrazole, arylidenehydrazines, and urea/thiourea, respectively.
The nonisolable carbohydrazide intermediates are formed firstly followed by the intermolecular nucleophilic attack of terminal amino group of hydrazide function on sp2 C6 rather than the sp3 C4 to give the ring adduct which was produced as a final product.
American Psychological Association (APA)
Said, Mohamed A.& Eldehna, Wagdy M.& Ghabbour, Hazem A.& Kabil, Maha M.& Al-shakliah, Nasser S.& Abdel-Aziz, Hatem A.. 2018. Solvent-Free Ring Cleavage Hydrazinolysis of Certain Biginelli Pyrimidines. Journal of Chemistry،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1182505
Modern Language Association (MLA)
Said, Mohamed A.…[et al.]. Solvent-Free Ring Cleavage Hydrazinolysis of Certain Biginelli Pyrimidines. Journal of Chemistry No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1182505
American Medical Association (AMA)
Said, Mohamed A.& Eldehna, Wagdy M.& Ghabbour, Hazem A.& Kabil, Maha M.& Al-shakliah, Nasser S.& Abdel-Aziz, Hatem A.. Solvent-Free Ring Cleavage Hydrazinolysis of Certain Biginelli Pyrimidines. Journal of Chemistry. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1182505
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1182505
