Synthesis and Biological Evaluation of 1,3,8-Triazaspiro[4.5]decane-2,4-dione Derivatives as Myelostimulators
Joint Authors
Baktybayeva, Lyailya
Yu, Valentina
Zazybin, Alexey
Zolotareva, Darya
Ten, Assel
Sagatbekova, Indira
Praliyev, Kaldybay
Seilkhanov, Tulegen
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Spiroconnected N-alkoxyalkylpiperidine hydantoins were obtained via the Strecker reaction of cyanohydrin with ammonium carbonate.
1,3,8-Triazaspiro[4.5]decane-2,4-diones have shown the myelostimulating activity in the artificially induced (with cyclophosphamide) myelodepressive syndrome.
The compounds significantly accelerated the regeneration of lymphocyte and granulocyte cell pool of bone marrow hematopoiesis.
American Psychological Association (APA)
Yu, Valentina& Ten, Assel& Baktybayeva, Lyailya& Sagatbekova, Indira& Praliyev, Kaldybay& Zolotareva, Darya…[et al.]. 2018. Synthesis and Biological Evaluation of 1,3,8-Triazaspiro[4.5]decane-2,4-dione Derivatives as Myelostimulators. Journal of Chemistry،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1182570
Modern Language Association (MLA)
Yu, Valentina…[et al.]. Synthesis and Biological Evaluation of 1,3,8-Triazaspiro[4.5]decane-2,4-dione Derivatives as Myelostimulators. Journal of Chemistry No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1182570
American Medical Association (AMA)
Yu, Valentina& Ten, Assel& Baktybayeva, Lyailya& Sagatbekova, Indira& Praliyev, Kaldybay& Zolotareva, Darya…[et al.]. Synthesis and Biological Evaluation of 1,3,8-Triazaspiro[4.5]decane-2,4-dione Derivatives as Myelostimulators. Journal of Chemistry. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1182570
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1182570
