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Practical Solution for Effective Whole-Body Magnetic Fluid Hyperthermia Treatment
Joint Authors
Chen, Guoping
Mamiya, Hiroaki
Jeyadevan, Balachandran
Takeda, Yoshihiko
Naka, Takashi
Kawazoe, Naoki
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Magnetic fluid hyperthermia therapy is considered as a promising treatment for cancers including unidentifiable metastatic cancers that are scattered across the whole body.
However, a recent study on heat transfer simulated on a human body model showed a serious side effect: occurrences of hot spots in normal tissues due to eddy current loss induced by variation in the irradiated magnetic field.
The indicated allowable upper limit of field amplitude Hac for constant irradiation over the entire human body corresponded to approximately 100 Oe at a frequency f of 25 kHz.
The limit corresponds to the value Hacf of 2.5 × 106 Oe·s−1 and is significantly lower than the conventionally accepted criteria of 6 × 107 Oe·s−1.
The present study involved evaluating maximum performance of conventional magnetic fluid hyperthermia cancer therapy below the afore-mentioned limit, and this was followed by discussing alternative methods not bound by standard frameworks by considering steady heat flow from equilibrium responses of stable nanoparticles.
Consequently, the clarified potentials of quasi-stable core-shell nanoparticles, dynamic alignment of easy axes, and short pulse irradiation indicate that the whole-body magnetic fluid hyperthermia treatment is still a possible candidate for future cancer therapy.
American Psychological Association (APA)
Mamiya, Hiroaki& Takeda, Yoshihiko& Naka, Takashi& Kawazoe, Naoki& Chen, Guoping& Jeyadevan, Balachandran. 2017. Practical Solution for Effective Whole-Body Magnetic Fluid Hyperthermia Treatment. Journal of Nanomaterials،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1182630
Modern Language Association (MLA)
Mamiya, Hiroaki…[et al.]. Practical Solution for Effective Whole-Body Magnetic Fluid Hyperthermia Treatment. Journal of Nanomaterials No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1182630
American Medical Association (AMA)
Mamiya, Hiroaki& Takeda, Yoshihiko& Naka, Takashi& Kawazoe, Naoki& Chen, Guoping& Jeyadevan, Balachandran. Practical Solution for Effective Whole-Body Magnetic Fluid Hyperthermia Treatment. Journal of Nanomaterials. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1182630
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1182630