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Photoregulation of Gold Nanoparticles Stabilized in a Diacetylenic Nanocapsule
Joint Authors
Chompoosor, Apiwat
Somjid, Saowalak
Kanokmedhakul, Somdej
Teerasong, Saowapak
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The results of releasing a drug in a burst are unpredictable and one of the inherent drawbacks of using nanocarriers.
Here, photoresponsive cationic gold nanoparticles to stabilize diacetylenic nanocapsules enabling photoregulated release of payloads are reported.
The fabrication of these nanocapsules relied on an electrostatic interaction of a negatively charged diacetylenic core and a positively charged gold nanoparticle shell.
Gold nanoparticles with photoresponsive ligands on their surfaces act as both hydrophobic core stabilizers and gatekeepers of the nanocapsules, while their polydiacetylene cores serve as hydrophobic drug carriers that can be tuned using UV irradiation.
The morphology of nanocapsules was analyzed using TEM and dynamic light scattering.
The resultant nanocapsules had a spherical shape with an average diameter of 152.9 ± 6.7 nm.
Upon UV irradiation, the nanocapsules lost their integrity and an encapsulated model compound was released through diffusion.
The release of a hydrophobic molecule was irradiation time dependent and thereby controllable.
This light-triggered release provides an alternative strategy for controlled drug delivery.
American Psychological Association (APA)
Somjid, Saowalak& Chompoosor, Apiwat& Kanokmedhakul, Somdej& Teerasong, Saowapak. 2017. Photoregulation of Gold Nanoparticles Stabilized in a Diacetylenic Nanocapsule. Journal of Nanomaterials،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1182816
Modern Language Association (MLA)
Somjid, Saowalak…[et al.]. Photoregulation of Gold Nanoparticles Stabilized in a Diacetylenic Nanocapsule. Journal of Nanomaterials No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1182816
American Medical Association (AMA)
Somjid, Saowalak& Chompoosor, Apiwat& Kanokmedhakul, Somdej& Teerasong, Saowapak. Photoregulation of Gold Nanoparticles Stabilized in a Diacetylenic Nanocapsule. Journal of Nanomaterials. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1182816
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1182816