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Carbon Nanofibers Coated with SiliconCalcium-Based Compounds for Medical Application
Joint Authors
Markowski, Jarosław
Smolka, Wojciech
Panek, Agnieszka
Jelen, Piotr
Paluszkiewicz, Czeslawa
Blazewicz, Marta
Dlugon, Elzbieta
Niemiec, Wiktor
Zagrajczuk, Barbara
Menaszek, Elzbieta
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-01
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The aim of this work was to develop a method for the manufacture of carbon nanofibers in the form of mats containing silicon and calcium compounds with potential biomedical application.
Carbon nanofibers (ECNF) were prepared from the electrospun polyacrylonitrile (PAN) nanofibers.
The electrospun polymer nanofibers were heat treated up to 1000°C to obtain carbon nanofibers.
The surface of ECNF was covered with a silica-calcium sol (ECNF+Si/Ca) by dip-coating technique followed by the stabilization process.
Both types of carbon nanofibers, i.e., the as-received and covered with the sol, were tested to confirm their osteoconductive properties.
Biological tests were performed, including genotoxicity, cytotoxicity, and alkaline phosphatase (ALP) activity.
Morphology of adhering cells to nanofiber surface was described.
The nanofibers were subjected to a bioactivity test in contact with SBF artificial plasma.
Biological tests have revealed that the nanofiber-modified ECNF+Si/Ca in contact with osteoblast cells were biocompatible, and the level of cytotoxicity was lower compared to the control.
The ALP activity of the modified nanofibers was higher than nonmodified nanofibers and indicates potential applications of such carbon materials in the form of mats as a substrate for bone tissue regeneration.
American Psychological Association (APA)
Smolka, Wojciech& Dlugon, Elzbieta& Jelen, Piotr& Niemiec, Wiktor& Panek, Agnieszka& Paluszkiewicz, Czeslawa…[et al.]. 2019. Carbon Nanofibers Coated with SiliconCalcium-Based Compounds for Medical Application. Journal of Nanomaterials،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1182891
Modern Language Association (MLA)
Smolka, Wojciech…[et al.]. Carbon Nanofibers Coated with SiliconCalcium-Based Compounds for Medical Application. Journal of Nanomaterials No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1182891
American Medical Association (AMA)
Smolka, Wojciech& Dlugon, Elzbieta& Jelen, Piotr& Niemiec, Wiktor& Panek, Agnieszka& Paluszkiewicz, Czeslawa…[et al.]. Carbon Nanofibers Coated with SiliconCalcium-Based Compounds for Medical Application. Journal of Nanomaterials. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1182891
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1182891