Peptide Self-Assembled Nanostructures for Drug Delivery Applications

Abstract EN

Peptide self-assembled nanostructures are very popular in many biomedical applications.

Drug delivery is one of the most promising applications among them.

The tremendous advantages for peptide self-assembled nanostructures include good biocompatibility, low cost, tunable bioactivity, high drug loading capacities, chemical diversity, specific targeting, and stimuli responsive drug delivery at disease sites.

Peptide self-assembled nanostructures such as nanoparticles, nanotubes, nanofibers, and hydrogels have been investigated by many researchers for drug delivery applications.

In this review, the underlying mechanisms for the self-assembled nanostructures based on peptides with different types and structures are introduced and discussed.

Peptide self-assembled nanostructures associated promising drug delivery applications such as anticancer drug and gene drug delivery are highlighted.

Furthermore, peptide self-assembled nanostructures for targeted and stimuli responsive drug delivery applications are also reviewed and discussed.