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Dose-Dependent Antimicrobial Activity of Silver Nanoparticles on Polycaprolactone Fibers against Gram-Positive and Gram-Negative Bacteria
Joint Authors
Espinosa-Cristóbal, L. F.
Reyes-López, Simón Yobanny
Cuevas-González, Juan Carlos
Donohue-Cornejo, Alejandro
Pazos-Ortiz, Erick
Roque-Ruiz, Jose Hafid
Hinojos-Márquez, Efrén Amador
López-Esparza, Juan
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-06
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The adhesion ability and adaptability of bacteria, coupled with constant use of the same bactericides, have made the increase in the diversity of treatments against infections necessary.
Nanotechnology has played an important role in the search for new ways to prevent and treat infections, including the use of metallic nanoparticles with antibacterial properties.
In this study, we worked on the design of a composite of silver nanoparticles (AgNPS) embedded in poly-epsilon-caprolactone nanofibers and evaluated its antimicrobial properties against various Gram-positive and Gram-negative microorganisms associated with drug-resistant infections.
Polycaprolactone-silver composites (PCL-AgNPs) were prepared in two steps.
The first step consisted in the reduction in situ of Ag+ ions using N,N-dimethylformamide (DMF) in tetrahydrofuran (THF) solution, and the second step involved the simple addition of polycaprolactone before electrospinning process.
Antibacterial activity of PCL-AgNPs nanofibers against E.
coli, S.
mutans, K.
pneumoniae, S.
aureus, P.
aeruginosa, and B.
subtilis was evaluated.
Results showed sensibility of E.
coli, K.
pneumoniae, S.
aureus, and P.
aeruginosa, but not for B.
subtilis and S.
mutans.
This antimicrobial activity of PCL-AgNPs showed significant positive correlations associated with the dose-dependent effect.
The antibacterial property of the PCL/Ag nanofibers might have high potential medical applications in drug-resistant infections.
American Psychological Association (APA)
Pazos-Ortiz, Erick& Roque-Ruiz, Jose Hafid& Hinojos-Márquez, Efrén Amador& López-Esparza, Juan& Donohue-Cornejo, Alejandro& Cuevas-González, Juan Carlos…[et al.]. 2017. Dose-Dependent Antimicrobial Activity of Silver Nanoparticles on Polycaprolactone Fibers against Gram-Positive and Gram-Negative Bacteria. Journal of Nanomaterials،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1183066
Modern Language Association (MLA)
Pazos-Ortiz, Erick…[et al.]. Dose-Dependent Antimicrobial Activity of Silver Nanoparticles on Polycaprolactone Fibers against Gram-Positive and Gram-Negative Bacteria. Journal of Nanomaterials No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1183066
American Medical Association (AMA)
Pazos-Ortiz, Erick& Roque-Ruiz, Jose Hafid& Hinojos-Márquez, Efrén Amador& López-Esparza, Juan& Donohue-Cornejo, Alejandro& Cuevas-González, Juan Carlos…[et al.]. Dose-Dependent Antimicrobial Activity of Silver Nanoparticles on Polycaprolactone Fibers against Gram-Positive and Gram-Negative Bacteria. Journal of Nanomaterials. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1183066
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183066