The Intricate Relationship between Type 2 Diabetes Mellitus (T2DM), Insulin Resistance (IR), and Nonalcoholic Fatty Liver Disease (NAFLD)
Joint Authors
Floria, Mariana
Tanase, Daniela-Maria
Gosav, Evelina Maria
Ouatu, Anca
Costea, Claudia Florida
Lacatusu, Cristina Mihaela
Maranduca, Minela Aida
Ciocoiu, Manuela
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-04
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) remain as one of the most global problematic metabolic diseases with rapidly increasing prevalence and incidence.
Epidemiological studies noted that T2DM patients have by two-fold increase to develop NAFLD, and vice versa.
This complex and intricate association is supported and mediated by insulin resistance (IR).
In this review, we discuss the NAFLD immunopathogenesis, connection with IR and T2DM, the role of screening and noninvasive tools, and mostly the impact of the current antidiabetic drugs on steatosis liver and new potential therapeutic targets.
American Psychological Association (APA)
Tanase, Daniela-Maria& Gosav, Evelina Maria& Costea, Claudia Florida& Ciocoiu, Manuela& Lacatusu, Cristina Mihaela& Maranduca, Minela Aida…[et al.]. 2020. The Intricate Relationship between Type 2 Diabetes Mellitus (T2DM), Insulin Resistance (IR), and Nonalcoholic Fatty Liver Disease (NAFLD). Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-16.
https://search.emarefa.net/detail/BIM-1183081
Modern Language Association (MLA)
Tanase, Daniela-Maria…[et al.]. The Intricate Relationship between Type 2 Diabetes Mellitus (T2DM), Insulin Resistance (IR), and Nonalcoholic Fatty Liver Disease (NAFLD). Journal of Diabetes Research No. 2020 (2020), pp.1-16.
https://search.emarefa.net/detail/BIM-1183081
American Medical Association (AMA)
Tanase, Daniela-Maria& Gosav, Evelina Maria& Costea, Claudia Florida& Ciocoiu, Manuela& Lacatusu, Cristina Mihaela& Maranduca, Minela Aida…[et al.]. The Intricate Relationship between Type 2 Diabetes Mellitus (T2DM), Insulin Resistance (IR), and Nonalcoholic Fatty Liver Disease (NAFLD). Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-16.
https://search.emarefa.net/detail/BIM-1183081
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183081
