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Noncoding RNAs in Diabetic Nephropathy: Pathogenesis, Biomarkers, and Therapy
Joint Authors
Lv, Jiarong
Wu, Yu
Mai, Yifeng
Bu, Shizhong
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-22
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The correlation between diabetes and systematic well-being on human life has long established.
As a common complication of diabetes, the prevalence of diabetic nephropathy (DN) has been increasing globally.
DN is known to be a major cause of end-stage kidney disease (ESKD).
Till now, the molecular mechanisms for DN have not been fully explored and the effective therapies are still lacking.
Noncoding RNAs are a class of RNAs produced by genome transcription that cannot be translated into proteins.
It has been documented that ncRNAs participate in the pathogenesis of DN by regulating inflammation, apoptosis, autophagy, cell proliferation, and other pathological processes.
In this review, the pathological roles and diagnostic and therapeutic potential of three types of ncRNAs (microRNA, long noncoding RNA, and circular RNA) in the progression of DN are summarized and illustrated.
American Psychological Association (APA)
Lv, Jiarong& Wu, Yu& Mai, Yifeng& Bu, Shizhong. 2020. Noncoding RNAs in Diabetic Nephropathy: Pathogenesis, Biomarkers, and Therapy. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1183087
Modern Language Association (MLA)
Lv, Jiarong…[et al.]. Noncoding RNAs in Diabetic Nephropathy: Pathogenesis, Biomarkers, and Therapy. Journal of Diabetes Research No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1183087
American Medical Association (AMA)
Lv, Jiarong& Wu, Yu& Mai, Yifeng& Bu, Shizhong. Noncoding RNAs in Diabetic Nephropathy: Pathogenesis, Biomarkers, and Therapy. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1183087
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183087