Association between Uric Acid and Bone Mineral Density in Postmenopausal Women with Type 2 Diabetes Mellitus in China: A Cross-Sectional Inpatient Study
Joint Authors
Zhao, Xin
Yu, Xiaofeng
Zhang, Xiaomei
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
To analyze the association between uric acid levels and bone mineral density in postmenopausal women with type 2 diabetes mellitus.
Methods.
We retrospectively analyzed 262 postmenopausal women with type 2 diabetes mellitus, to assess uric acid levels and bone mineral density using the T score of dual-energy X-ray absorptiometry.
Results.
(1) Women in the osteoporosis group demonstrated higher uric acid levels and lower estimated glomerular filtration rate (p<0.05, respectively).
(2) Uric acid levels were positively correlated with the hip and lumbar spine bone mineral density and T score (r=0.17, p<0.05; r=0.25, p<0.05; r=0.17, p<0.05; and r=0.28, p<0.05, respectively).
Meanwhile, there was a positive relation between estimated glomerular filtration rate and hip bone mineral density (r=0.22, p<0.05).
(3) Logistic regression analysis showed that age, body mass index, and diabetic duration are independent risk factors for osteoporosis in postmenopausal women with type 2 diabetes mellitus.
The level of estimated glomerular filtration rate and uric acid levels were not independent effect factors for osteoporosis in menopausal women.
Conclusion.
Uric acid levels are neither a protective factor nor a risk factor for osteoporosis in women with type 2 diabetes mellitus.
American Psychological Association (APA)
Zhao, Xin& Yu, Xiaofeng& Zhang, Xiaomei. 2020. Association between Uric Acid and Bone Mineral Density in Postmenopausal Women with Type 2 Diabetes Mellitus in China: A Cross-Sectional Inpatient Study. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1183093
Modern Language Association (MLA)
Zhao, Xin…[et al.]. Association between Uric Acid and Bone Mineral Density in Postmenopausal Women with Type 2 Diabetes Mellitus in China: A Cross-Sectional Inpatient Study. Journal of Diabetes Research No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1183093
American Medical Association (AMA)
Zhao, Xin& Yu, Xiaofeng& Zhang, Xiaomei. Association between Uric Acid and Bone Mineral Density in Postmenopausal Women with Type 2 Diabetes Mellitus in China: A Cross-Sectional Inpatient Study. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1183093
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183093