Evaluation and Optimization of Paper-Based SERS Substrate for Potential Label-Free Raman Analysis of Seminal Plasma
Joint Authors
Du, Shengrong
Huang, Zufang
Cao, Gang
Sun, Yan
Li, Yongzeng
Lin, Juqiang
Lei, Jinping
Feng, Shangyuan
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Characterization and optimization of paper SERS substrate were performed in detail, in which morphologies and distribution of silver nanoparticles (AgNPs) on the paper substrate pretreated with different concentrations of NaCl and the subsequent soaking with colloidal AgNPs for different period of time were evaluated.
Our results show that both NaCl concentration and soaking time with AgNPs have a significant influence on SERS enhancement, showing that an optimal EF of 2.27 × 107 was achieved when the paper substrate was treated with 20 mM NaCl and one-hour soak with AgNPs.
Moreover, seminal plasma (SP) was specifically selected to evaluate the performance of paper-based SERS substrate for potential clinical detection and diagnosis.
The optimization of the paper SERS substrate demonstrates potential applications in reliable on-site detection of SP and clinical diagnosis of fertility-related diseases as well.
American Psychological Association (APA)
Huang, Zufang& Cao, Gang& Sun, Yan& Du, Shengrong& Li, Yongzeng& Feng, Shangyuan…[et al.]. 2017. Evaluation and Optimization of Paper-Based SERS Substrate for Potential Label-Free Raman Analysis of Seminal Plasma. Journal of Nanomaterials،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1183096
Modern Language Association (MLA)
Huang, Zufang…[et al.]. Evaluation and Optimization of Paper-Based SERS Substrate for Potential Label-Free Raman Analysis of Seminal Plasma. Journal of Nanomaterials No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1183096
American Medical Association (AMA)
Huang, Zufang& Cao, Gang& Sun, Yan& Du, Shengrong& Li, Yongzeng& Feng, Shangyuan…[et al.]. Evaluation and Optimization of Paper-Based SERS Substrate for Potential Label-Free Raman Analysis of Seminal Plasma. Journal of Nanomaterials. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1183096
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183096