Two to Tango: Dialogue between Adaptive and Innate Immunity in Type 1 Diabetes
Joint Authors
Sun, Chenglin
Gang, Xiaokun
Wang, Guixia
Sun, Lin
Xi, Shugang
He, Guangyu
Li, Zhuo
Guo, Weiying
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-31
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Type 1 diabetes mellitus (T1DM) is a long-term and chronic autoimmune disorder, in which the immune system attacks the pancreatic β-cells.
Both adaptive and innate immune systems are involved in T1DM development.
Both B-cells and T-cells, including CD4+ and CD8+ T-cells, as well as other T-cell subsets, could affect onset of autoimmunity.
Furthermore, cells involved in innate immunity, including the macrophages, dendritic cells, and natural killer (NK) cells, could also accelerate or decelerate T1DM development.
In this review, the crosstalk and function of immune cells in the pathogenesis of T1DM, as well as the corresponding therapeutic interventions, are discussed.
American Psychological Association (APA)
Sun, Lin& Xi, Shugang& He, Guangyu& Li, Zhuo& Gang, Xiaokun& Sun, Chenglin…[et al.]. 2020. Two to Tango: Dialogue between Adaptive and Innate Immunity in Type 1 Diabetes. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1183107
Modern Language Association (MLA)
Sun, Lin…[et al.]. Two to Tango: Dialogue between Adaptive and Innate Immunity in Type 1 Diabetes. Journal of Diabetes Research No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1183107
American Medical Association (AMA)
Sun, Lin& Xi, Shugang& He, Guangyu& Li, Zhuo& Gang, Xiaokun& Sun, Chenglin…[et al.]. Two to Tango: Dialogue between Adaptive and Innate Immunity in Type 1 Diabetes. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1183107
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183107
