Clinical Features and Risk Factors of ICU Admission for COVID-19 Patients with Diabetes
Joint Authors
Huang, Jun
Lei, Ming
Lin, Kashuai
Pi, Yaoqiu
Huang, Xiaomei
Fan, Lixin
Liu, Riguang
Shao, Xinning
Hu, Kaiyuan
Yang, Liuping
Qin, Shuguang
He, Feng
Liu, Lin
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-15
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Introduction.
Previous studies of coronavirus disease 2019 (COVID-19) have focused on the general population.
However, diabetes (DM) as one of the most common comorbidities is rarely studied in detail.
This study is aimed at describing clinical characteristics and determining risk factors of ICU admission for COVID-19 patients with DM.
Methods.
Data were extracted from 288 adult patients with laboratory-confirmed COVID-19 from Guangzhou Eighth People’s Hospital.
Demographic characteristics, laboratory results, radiographic findings, complications, and treatments were collected and compared between DM and non-DM groups.
Binary logistic regression was used to identify the risk factors associated with ICU admission for COVID-19 patients with DM or non-DM.
Results.
COVID-19 patients with DM showed as older ages, higher levels of C-reactive protein (CRP), myoglobin, alanine transaminase (ALT), and aspartate transaminase (AST).
They were also more prone to transfer to the intensive care unit (ICU) for treatment.
Multiple regression analysis showed that the following were the independent risk factors for COVID-19 patients with DM that received ICU admission: each 1-year increase in age (odds ratio (OR), 1.07; 95% CI, 1.02-1.13; P=0.007), respiratory rate over 24 times per minute (OR, 5.22; 95% CI, 2.26-16.58; P=0.016), HbA1c greater than 7% (OR, 4.58; 95% CI, 1.82-10.55; P=0.012), and AST higher than 40 U/L (OR, 2.96; 95% CI, 1.58-8.85; P=0.022).
In addition, each 1-year increase in age (OR, 1.05; 95% CI, 1.01-1.10; P=0.006), diarrhea (OR, 4.62; 95% CI, 2.01-9.36; P=0.022), respiratory rate over 24 times per minute (OR, 5.13; 95% CI, 1.18-16.82; P=0.035), CRP greater than 10 mg/L (OR, 5.19; 95% CI, 1.37-13.25, P=0.009), and TnI higher than 0.03 μg/L (OR, 6.48; 95% CI, 1.17-21.38; P=0.036) were risk factors for ICU admission of COVID-19 patients with non-DM.
Conclusions.
The older age, respiratory rate over 24 times per minute, HbA1c greater than 7%, and AST higher than 40 U/L were risk factors of ICU admission for COVID-19 patients with diabetes.
Investigating and monitoring these factors could assist in the risk stratification of COVID-19 patients with DM at an early stage.
American Psychological Association (APA)
Lei, Ming& Lin, Kashuai& Pi, Yaoqiu& Huang, Xiaomei& Fan, Lixin& Huang, Jun…[et al.]. 2020. Clinical Features and Risk Factors of ICU Admission for COVID-19 Patients with Diabetes. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1183192
Modern Language Association (MLA)
Lei, Ming…[et al.]. Clinical Features and Risk Factors of ICU Admission for COVID-19 Patients with Diabetes. Journal of Diabetes Research No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1183192
American Medical Association (AMA)
Lei, Ming& Lin, Kashuai& Pi, Yaoqiu& Huang, Xiaomei& Fan, Lixin& Huang, Jun…[et al.]. Clinical Features and Risk Factors of ICU Admission for COVID-19 Patients with Diabetes. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1183192
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183192