Evaluation of Foveal and Parafoveal Microvascular Changes Using Optical Coherence Tomography Angiography in Type 2 Diabetes Patients without Clinical Diabetic Retinopathy in South Korea
Joint Authors
Park, Young Gun
Kim, Minhee
Roh, Young Jung
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The aim of this study was to investigate foveal and parafoveal microvascular changes in retinal vascular plexuses in patients with type 2 diabetes mellitus (DM) without clinical diabetic retinopathy (NDR) using optical coherence tomography angiography (OCTA) in South Korea.
We included 64 patients in the NDR group and included 48 healthy control subjects for comparison.
All subjects underwent ocular examination with visual acuity and wide-field fundus photos.
Foveal and parafoveal vessel density and foveal avascular zone (FAZ) area (mm2) in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) were analyzed.
Foveal vessel densities in both the SCP and DCP were decreased in the NDR group compared to the controls (p=0.034 and 0.001, respectively).
Vessel densities in the superior and inferior parafoveae in the DCP were decreased in the NDR group compared to the controls (p=0.006 and 0.034, respectively).
The FAZs of the SCP and DCP were significantly different between the NDR group and the controls (p=0.003 and 0.001, respectively).
The average vessel densities of the SCP and DCP were not correlated with HbA1c, serum creatinine, or the duration of DM in the NDR group.
We demonstrated that OCTA can identify early-stage DR before the manifestation of clinically apparent retinopathy in diabetic eyes.
Diabetic patients without clinical DR have microvascular alterations (foveal vessel density, parts of the parafovea, and enlarged FAZ) in the SCP and DCP.
Our results suggest that OCTA might be a promising tool for early detection of eyes with DR.
American Psychological Association (APA)
Park, Young Gun& Kim, Minhee& Roh, Young Jung. 2020. Evaluation of Foveal and Parafoveal Microvascular Changes Using Optical Coherence Tomography Angiography in Type 2 Diabetes Patients without Clinical Diabetic Retinopathy in South Korea. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1183255
Modern Language Association (MLA)
Park, Young Gun…[et al.]. Evaluation of Foveal and Parafoveal Microvascular Changes Using Optical Coherence Tomography Angiography in Type 2 Diabetes Patients without Clinical Diabetic Retinopathy in South Korea. Journal of Diabetes Research No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1183255
American Medical Association (AMA)
Park, Young Gun& Kim, Minhee& Roh, Young Jung. Evaluation of Foveal and Parafoveal Microvascular Changes Using Optical Coherence Tomography Angiography in Type 2 Diabetes Patients without Clinical Diabetic Retinopathy in South Korea. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1183255
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183255