Relationship between Maternal Central Obesity and the Risk of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of Cohort Studies
Joint Authors
Yao, Da
Chang, Qing
Wu, Qi-Jun
Gao, Shan-Yan
Zhao, Huan
Liu, Ya-Shu
Jiang, Yu-Ting
Zhao, Yu-Hong
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-03
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Objective.
Nowadays, body mass index (BMI) is used to evaluate the risk stratification of obesity-related pregnancy complications in clinics.
However, BMI cannot reflect fat distribution or the proportion of adipose to nonadipose tissue.
The objective of this study is to evaluate the association of maternal first or second trimester central obesity with the risk of GDM.
Research Design and Methods.
We searched in PubMed, Embase, and Web of Science for English-language medical literature published up to 12 May 2019.
Cohort studies were only included in the search.
Abdominal subcutaneous fat thickness, waist circumference, waist-hip ratio or body fat distribution were elected as measures of maternal central obesity, and all diagnostic criteria for GDM were accepted.
The random effect meta-analysis was performed to evaluate the relationship between central obesity and the risk of GDM.
Results.
A total of 11 cohort studies with an overall sample size of 27,675 women and 2,226 patients with GDM were included in the analysis.
The summary estimate of GDM risk in the central obesity pregnant women was 2.76 (95% confidence interval [CI]: 2.35–3.26) using the adjusted odds ratio (OR).
The degree of heterogeneity among the studies was low (I2=14.4, P=0.307).
The subgroup analyses showed that heterogeneity was affected by selected study characteristics (methods of exposure and trimesters).
After adjusting for potential confounds, the OR of adjusted BMI was significant (OR=3.07, 95% CI: 2.35–4.00).
Conclusions.
Our findings indicate that the risk of GDM was positively associated with maternal central obesity.
American Psychological Association (APA)
Yao, Da& Chang, Qing& Wu, Qi-Jun& Gao, Shan-Yan& Zhao, Huan& Liu, Ya-Shu…[et al.]. 2020. Relationship between Maternal Central Obesity and the Risk of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of Cohort Studies. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1183264
Modern Language Association (MLA)
Yao, Da…[et al.]. Relationship between Maternal Central Obesity and the Risk of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of Cohort Studies. Journal of Diabetes Research No. 2020 (2020), pp.1-12.
https://search.emarefa.net/detail/BIM-1183264
American Medical Association (AMA)
Yao, Da& Chang, Qing& Wu, Qi-Jun& Gao, Shan-Yan& Zhao, Huan& Liu, Ya-Shu…[et al.]. Relationship between Maternal Central Obesity and the Risk of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of Cohort Studies. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1183264
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183264