Cognitive Function Is Impaired in Patients with Recently Diagnosed Type 2 Diabetes, but Not Type 1 Diabetes
Joint Authors
Müssig, Karsten
van Gemert, Theresa
Wölwer, Wolfgang
Weber, Katharina S.
Hoyer, Annika
Strassburger, Klaus
Bohnau, Nora T.
Brüggen, Marie A.
Ovelgönne, Katharina
Gössmann, Eva-Maria
Burkart, Volker
Szendroedi, Julia
Roden, Michael
Masaki, Takayuki
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-09
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
To test whether cognitive function is impaired in early states of diabetes and to identify possible risk factors for cognitive impairment.
Methods.
A cross-sectional analysis within the German Diabetes Study included patients with type 1 or type 2 diabetes within the first year after diagnosis or five years after study inclusion and metabolically healthy individuals.
Participants underwent comprehensive metabolic phenotyping and testing of different domains of cognitive function.
Linear regression models were used to compare cognition test outcomes and to test associations between cognitive function and possible influencing factors within the groups.
Results.
In participants with recently diagnosed diabetes, verbal memory was poorer in patients with type 2 diabetes (P=0.029), but not in type 1 diabetes (P=0.156), when compared to healthy individuals.
Five years after diagnosis, type 2 diabetes patients also showed lower verbal memory than those with type 1 diabetes (P=0.012).
In addition to crystallized intelligence, a higher body mass index among individuals with recently diagnosed type 2 diabetes and male sex among individuals with recently diagnosed type 1 diabetes were associated with impaired verbal memory (all P<0.05).
Conclusion.
Verbal memory is impaired in individuals with recently diagnosed type 2 diabetes and likely associated with higher body mass.
This trial is registered with the trial registration number NCT01055093.
American Psychological Association (APA)
van Gemert, Theresa& Wölwer, Wolfgang& Weber, Katharina S.& Hoyer, Annika& Strassburger, Klaus& Bohnau, Nora T.…[et al.]. 2018. Cognitive Function Is Impaired in Patients with Recently Diagnosed Type 2 Diabetes, but Not Type 1 Diabetes. Journal of Diabetes Research،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1183268
Modern Language Association (MLA)
van Gemert, Theresa…[et al.]. Cognitive Function Is Impaired in Patients with Recently Diagnosed Type 2 Diabetes, but Not Type 1 Diabetes. Journal of Diabetes Research No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1183268
American Medical Association (AMA)
van Gemert, Theresa& Wölwer, Wolfgang& Weber, Katharina S.& Hoyer, Annika& Strassburger, Klaus& Bohnau, Nora T.…[et al.]. Cognitive Function Is Impaired in Patients with Recently Diagnosed Type 2 Diabetes, but Not Type 1 Diabetes. Journal of Diabetes Research. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1183268
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183268