Impaired Glomerular Filtration Rate in Type 2 Diabetes Mellitus Subjects: A Nationwide Cross-Sectional Study in Thailand
Joint Authors
Satirapoj, Bancha
Supasyndh, Ouppatham
Nata, Naowanit
Rangsin, Ram
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
Type 2 diabetic mellitus (T2DM) patients with impaired renal function have a higher risk of mortality, and often progress to end-stage renal disease.
The study aims to determine the prevalence of kidney disease and investigate the relationship between various factors and impaired renal function in a large population of patients with T2DM.
Methods.
We conducted a cross-sectional study among 30,377 patients from a nationwide diabetes study involving 602 Thai hospitals.
Impaired glomerular filtration rate (GFR) was defined as <60 mL/min per 1.73 m2.
Multivariate logistic regression was used to determine the association between standard risk factors and impaired GFR.
Results.
The prevalence of impaired GFR in a T2DM population was 39.2%.
After adjusting for multiple risk factors, advanced age (adjusted OR 11.69 (95%CI=3.13 to 43.61)), macroalbuminuria (adjusted OR 3.54 (95%CI=1.50 to 8.40)), high serum uric acid (adjusted OR 2.06 (95%CI=1.73 to 2.46)), systolic BP 130-139 mmHg (adjusted OR 3.21 (95%CI=1.30 to 7.96)), hemoglobinA1C (HA1C) <6% (adjusted OR 3.71 (95%CI=1.65 to 8.32)), and HA1C >7% (adjusted OR 2.53 (95%CI=1.38 to 4.63)) were found to be associated with a significantly increased risk of impaired GFR among T2DM patients.
Conclusion.
Almost 40% of patients with T2DM in a nationwide cross-sectional study in Thailand had impaired GFR.
Advanced age, albuminuria, hyperuricemia, hypertension, HA1C <6%, and HA1C >7% were independently associated with increased prevalence of impaired GFR.
American Psychological Association (APA)
Nata, Naowanit& Rangsin, Ram& Supasyndh, Ouppatham& Satirapoj, Bancha. 2020. Impaired Glomerular Filtration Rate in Type 2 Diabetes Mellitus Subjects: A Nationwide Cross-Sectional Study in Thailand. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1183273
Modern Language Association (MLA)
Nata, Naowanit…[et al.]. Impaired Glomerular Filtration Rate in Type 2 Diabetes Mellitus Subjects: A Nationwide Cross-Sectional Study in Thailand. Journal of Diabetes Research No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1183273
American Medical Association (AMA)
Nata, Naowanit& Rangsin, Ram& Supasyndh, Ouppatham& Satirapoj, Bancha. Impaired Glomerular Filtration Rate in Type 2 Diabetes Mellitus Subjects: A Nationwide Cross-Sectional Study in Thailand. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1183273
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183273