Recent Advances in the Development of Vaccines for Diabetes, Hypertension, and Atherosclerosis
Joint Authors
Su, B.
Lu, Kongye
Meng, Xiuxiang
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Vaccines are commonly used in the prevention of infectious diseases.
The basic principle of vaccination is to use specific antigens, endogenous or exogenous to stimulate immunity against the specific antigens or cells producing them.
Autoantigen or oligo vaccination has been used for disease animal models.
More recently humanized monoclonal antibodies have been successfully used for the treatment of neoplastic disorders or familial hypercholesterolemia.
Humanized monoclonal antibody therapy needs repeated injection, and the therapy is expensive.
Therapeutic vaccination can lead to persistent immunized or immune tolerant against the therapeutic molecule(s) or site.
However, immunization against those endogenous substances may also elicit persistent autoimmune reaction or destruction that do harm to health.
Therefore, rigorous studies are needed before any clinical application.
In this review, we briefly reviewed vaccines used in protection against common metabolic diseases including atherosclerosis, hypertension, and diabetes mellitus.
American Psychological Association (APA)
Lu, Kongye& Su, B.& Meng, Xiuxiang. 2018. Recent Advances in the Development of Vaccines for Diabetes, Hypertension, and Atherosclerosis. Journal of Diabetes Research،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1183285
Modern Language Association (MLA)
Lu, Kongye…[et al.]. Recent Advances in the Development of Vaccines for Diabetes, Hypertension, and Atherosclerosis. Journal of Diabetes Research No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1183285
American Medical Association (AMA)
Lu, Kongye& Su, B.& Meng, Xiuxiang. Recent Advances in the Development of Vaccines for Diabetes, Hypertension, and Atherosclerosis. Journal of Diabetes Research. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1183285
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183285