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Metabolic and Nutritional Characteristics in Middle-Aged and Elderly Sarcopenia Patients with Type 2 Diabetes
Joint Authors
Sun, Mingxiao
Hu, Jing
He, Qinghua
Wang, Xiuzhi
Yang, Caizhe
Zhuang, Xiaoming
Yue, Yanfen
Jing, Hongjiang
Guo, Lixin
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Sarcopenia is considered to be a new complication of type 2 diabetes (T2DM) leading to increased risk of adverse outcome.
We performed a survey to evaluate glucose metabolism and nutritional status in sarcopenia patients with T2DM.
Diabetic participants aged ≥50 years were grouped into a probable sarcopenia group with low muscle strength (n=405) and a nonsarcopenia group with normal muscle strength (n=720) according to the revised recommendations from EWGSOP2 (2018).
Compared to the controls, the probable sarcopenia participants were older and had lower waist-to-hip ratio and BMI, longer diabetes duration, higher fasting plasma glucose level and glycosylated hemoglobin (HbA1c), decreased estimated glomerular filtration rate and lower bone mineral content, lower fatless upper arm circumference, lower appendicular skeletal muscle mass index (ASMI), and muscle quality in both genders.
Multivariable logistic regression analysis showed increased age, male, low BMI, and increased HbA1c, combined with diabetic nephropathy and decreased serum albumin levels, were risk factors associated with low muscle strength in diabetes patients.
In conclusion, diabetic patients with sarcopenia had worse glucose metabolism and nutritional status, decreased renal function and reduced muscle quality ,and muscle mass with a greater likelihood of osteoporosis, who need an overall health management to improve outcomes.
This clinical trial registration is registered with the Chinese Clinical Trial Registry, ChiCTR-EOC-15006901.
American Psychological Association (APA)
He, Qinghua& Wang, Xiuzhi& Yang, Caizhe& Zhuang, Xiaoming& Yue, Yanfen& Jing, Hongjiang…[et al.]. 2020. Metabolic and Nutritional Characteristics in Middle-Aged and Elderly Sarcopenia Patients with Type 2 Diabetes. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1183320
Modern Language Association (MLA)
He, Qinghua…[et al.]. Metabolic and Nutritional Characteristics in Middle-Aged and Elderly Sarcopenia Patients with Type 2 Diabetes. Journal of Diabetes Research No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1183320
American Medical Association (AMA)
He, Qinghua& Wang, Xiuzhi& Yang, Caizhe& Zhuang, Xiaoming& Yue, Yanfen& Jing, Hongjiang…[et al.]. Metabolic and Nutritional Characteristics in Middle-Aged and Elderly Sarcopenia Patients with Type 2 Diabetes. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1183320
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183320