Preoperative Blood Glucose Level Predicts Postsurgical Gastroparesis Syndrome after Subtotal Gastrectomy: Development of an Individualized Usable Nomogram
Joint Authors
Mao, Chenchen
Liu, Xin
Huang, Yunshi
Shi, Mingming
Meng, Weiyang
Xu, Libin
Chen, Weisheng
Hu, Yuanbo
Yang, Xinxin
Chen, Xiaodong
Shen, Xian
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Postsurgical gastroparesis syndrome (PGS) after subtotal gastrectomy imposes significant social and economic burdens.
We aimed to investigate the relationship between preoperative blood glucose level and PGS and develop a nomogram for individualized prediction.
Patients and Methods.
We retrospectively analyzed 633 patients with gastric cancer who underwent subtotal gastrectomy.
Preoperative blood glucose levels were evaluated via receiver operating characteristic (ROC) curve analysis.
Chi-squared tests and multivariable logistic regression analyses were used to develop a predictive model for PGS, presented as a nomogram, which was assessed for its clinical usefulness.
Results.
Thirty-eight of 633 patients were diagnosed with PGS.
Based on the ROC curve analysis, the preoperative blood glucose cutoff value for PGS was 6.25 mmol/L.
The predictors of PGS included preoperative hyperglycemia (odds ratio (OR) 2.3, P=0.03), body mass index (BMI; OR 0.21, P=0.14 for BMI<18.5 and OR 3.0, P=0.004 for BMI>24), and the anastomotic method (OR 7.3, P=0.001 for Billroth II and OR 5.9, P=0.15 for Roux-en-Y).
The predictive model showed good discrimination ability, with a C-index of 0.710, and was clinically useful.
Conclusions.
Preoperative hyperglycemia effectively predicts PGS.
We present a nomogram incorporating the preoperative blood glucose level, BMI, anastomotic method, and tumor size, for individualized prediction of PGS.
American Psychological Association (APA)
Mao, Chenchen& Liu, Xin& Huang, Yunshi& Shi, Mingming& Meng, Weiyang& Xu, Libin…[et al.]. 2020. Preoperative Blood Glucose Level Predicts Postsurgical Gastroparesis Syndrome after Subtotal Gastrectomy: Development of an Individualized Usable Nomogram. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1183332
Modern Language Association (MLA)
Mao, Chenchen…[et al.]. Preoperative Blood Glucose Level Predicts Postsurgical Gastroparesis Syndrome after Subtotal Gastrectomy: Development of an Individualized Usable Nomogram. Journal of Diabetes Research No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1183332
American Medical Association (AMA)
Mao, Chenchen& Liu, Xin& Huang, Yunshi& Shi, Mingming& Meng, Weiyang& Xu, Libin…[et al.]. Preoperative Blood Glucose Level Predicts Postsurgical Gastroparesis Syndrome after Subtotal Gastrectomy: Development of an Individualized Usable Nomogram. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1183332
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183332