Development and Validation of a Hypoglycemia Risk Model for Intensive Insulin Therapy in Patients with Type 2 Diabetes
Joint Authors
Zhang, Cang
Hu, Xiling
Xu, Weiran
Lin, Shuo
Ling, Cong
Chen, Miaoxia
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Aims.
To develop a simple hypoglycemic prediction model to evaluate the risk of hypoglycemia during hospitalization in patients with type 2 diabetes treated with intensive insulin therapy.
Methods.
We performed a cross-sectional chart review study utilizing the electronic database of the Third Affiliated Hospital of Sun Yat-sen University, and included 257 patients with type 2 diabetes undergoing intensive insulin therapy in the Department of Endocrinology and Metabolism.
Logistic regression analysis was used to derive the clinical prediction rule with hypoglycemia (blood glucose≤3.9 mmol/L) as the main result, and internal verification was performed.
Results.
In the derivation cohort, the incidence of hypoglycemia was 51%.
The final model selected included three variables: fasting insulin, fasting blood glucose, and total treatment time.
The area under the curve (AUC) of this model was 0.666 (95% CI: 0.594–0.738, P<0.001).
Conclusions.
The model’s hypoglycemia prediction and the actual occurrence are in good agreement.
The variable data was easy to obtain and the evaluation method was simple, which could provide a reference for the prevention and treatment of hypoglycemia and screen patients with a high risk of hypoglycemia.
American Psychological Association (APA)
Hu, Xiling& Xu, Weiran& Lin, Shuo& Zhang, Cang& Ling, Cong& Chen, Miaoxia. 2020. Development and Validation of a Hypoglycemia Risk Model for Intensive Insulin Therapy in Patients with Type 2 Diabetes. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1183365
Modern Language Association (MLA)
Hu, Xiling…[et al.]. Development and Validation of a Hypoglycemia Risk Model for Intensive Insulin Therapy in Patients with Type 2 Diabetes. Journal of Diabetes Research No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1183365
American Medical Association (AMA)
Hu, Xiling& Xu, Weiran& Lin, Shuo& Zhang, Cang& Ling, Cong& Chen, Miaoxia. Development and Validation of a Hypoglycemia Risk Model for Intensive Insulin Therapy in Patients with Type 2 Diabetes. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1183365
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183365