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Outcomes of Children and Adolescents Admitted with Diabetic Ketoacidosis at Kenyatta National Hospital (KNH), Kenya
Joint Authors
Laigong, Paul
Musoma, Sophie Nyaombe
Omar, Anjumanara
Mutai, Beatrice Chepngeno
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-20
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication that mainly occurs in patients with type 1 diabetes mellitus and is the foremost cause of death in these children.
Overall mortality in children with DKA varies from 3.4% to 13.4% in developing countries.
There is a need to understand outcomes among children with DKA in sub-Saharan African countries.
Objective.
To determine the death rate and clinical outcomes of children and adolescents aged 0-18 years managed for DKA at Kenyatta National Hospital (KNH).
Study Methods.
This was a retrospective study carried out among children aged 0–18 years admitted with DKA at KNH between February 2013 and February 2018.
The study site was the central records department at KNH.
The inclusion criteria were children aged 0-18 years admitted with a diagnosis of DKA based on the ISPAD guidelines biochemical criteria.
Results.
Out of the 159 files reviewed, the median age of children was 13 years (IQR 10-15).
41.1% of patients had severe DKA while 35.7% had moderate DKA.
We reported a mortality of 6.9% while 93.1% of children recovered and were discharged home.
The median duration of hospital stay was 8 days.
High risk of mortality was reported among children who had high serum creatinine (OR 5.8 (95% CI 1.6-21.2)), decreased urine output (OR 9.0 (95% CI 2.2-37.3)), and altered level of consciousness (OR 5.2 (95% CI 1.1-25.1)).
Conclusion.
DKA-associated mortality in our study was low at 6.9%.
High serum creatinine, decreased urine output, and altered level of consciousness were associated with a significantly higher risk of mortality.
American Psychological Association (APA)
Musoma, Sophie Nyaombe& Omar, Anjumanara& Mutai, Beatrice Chepngeno& Laigong, Paul. 2020. Outcomes of Children and Adolescents Admitted with Diabetic Ketoacidosis at Kenyatta National Hospital (KNH), Kenya. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1183514
Modern Language Association (MLA)
Musoma, Sophie Nyaombe…[et al.]. Outcomes of Children and Adolescents Admitted with Diabetic Ketoacidosis at Kenyatta National Hospital (KNH), Kenya. Journal of Diabetes Research No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1183514
American Medical Association (AMA)
Musoma, Sophie Nyaombe& Omar, Anjumanara& Mutai, Beatrice Chepngeno& Laigong, Paul. Outcomes of Children and Adolescents Admitted with Diabetic Ketoacidosis at Kenyatta National Hospital (KNH), Kenya. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1183514
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183514