Four Plasma Glucose and Insulin Responses to a 75 g OGTT in Healthy Young Japanese Women
Joint Authors
Takahashi, Kei
Nakamura, Hidetaka
Sato, Hiroshi
Matsuda, Hideto
Takada, Kazuo
Tsuji, Tomiko
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The incidence of diabetes has been gradually increasing, not only in middle-aged individuals but also in young individuals.
However, insulin and glucose patterns have not been investigated in apparently healthy young individuals, as they are typically grouped as controls.
In this study, we investigated and classified glucose and insulin patterns in healthy young women.
Sixty-two nonobese women without metabolic disease were recruited.
The subjects underwent a 75 g oral glucose tolerance test (OGTT), physical measurements, and a biochemical examination.
Two subjects displayed impaired glucose tolerance.
The 62 subjects were categorized into four patterns by plasma glucose and insulin peak time during OGTT: normal type (n=39), insulin-late type (n=11), insulin- and glucose-late type (n=7), and insulin-very late type (n=5).
OGTT glucose and insulin levels at all time points, insulinogenic index, HOMA-IR, and glucose area under the curve (AUC) significantly differed among the four groups.
However, insulin AUC did not significantly differ.
We did not detect significant differences in body condition or biochemical measurements.
Our study demonstrated that some healthy young individuals might have delayed insulin secretion by OGTT.
Early detection of altered glucose metabolism might be helpful to improve lifestyle choices and prevent progression to diabetes.
American Psychological Association (APA)
Takahashi, Kei& Nakamura, Hidetaka& Sato, Hiroshi& Matsuda, Hideto& Takada, Kazuo& Tsuji, Tomiko. 2018. Four Plasma Glucose and Insulin Responses to a 75 g OGTT in Healthy Young Japanese Women. Journal of Diabetes Research،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1183718
Modern Language Association (MLA)
Takahashi, Kei…[et al.]. Four Plasma Glucose and Insulin Responses to a 75 g OGTT in Healthy Young Japanese Women. Journal of Diabetes Research No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1183718
American Medical Association (AMA)
Takahashi, Kei& Nakamura, Hidetaka& Sato, Hiroshi& Matsuda, Hideto& Takada, Kazuo& Tsuji, Tomiko. Four Plasma Glucose and Insulin Responses to a 75 g OGTT in Healthy Young Japanese Women. Journal of Diabetes Research. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1183718
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183718