Correlation between Structures and Antioxidant Activities of PolyvinylpyrrolidoneGarcinia mangostana L. Extract Composite Nanofiber Mats Prepared Using Electrospinning
Joint Authors
Sriyanti, Ida
Edikresnha, Dhewa
Rahma, Annisa
Munir, Muhammad Miftahul
Rachmawati, Heni
Khairurrijal,
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-18
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Nanofiber mats of polyvinyl(pyrrolidone) (PVP) with Garcinia mangostana extract (GME) as the encapsulated drug have been developed using electrospinning.
SEM images of all electrospun PVP/GME composite nanofiber mats showed that they had similar and smooth morphology, no beads, and spindle shape.
Its average diameter decreased and its surface area therefore increased with the decrease of its PVP concentration.
The benefit of high surface area is obvious in drug delivery systems for poorly water-soluble drugs.
Their FTIR spectra indicated that PVP and GME interacted intermolecularly via hydrogen bonds in the composite nanofiber mats.
A conformational change in the C-H chain of PVP occurred in the composite nanofiber mats due to the intermolecular interactions.
Their XRD patterns confirmed that they were amorphous because of amorphization during electrospinning.
The XRD analyses also strengthened the FTIR studies; namely, GME and PVP formed intermolecular interactions in the electrospun composite nanofiber mats.
As a result, GME as the encapsulated drug was molecularly dispersed in the electrospun PVP nanofiber matrix that functioned as a drug delivery system.
From the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, the composite nanofiber mats exhibited very high antioxidant activities despite having been exposed to high voltage during electrospinning.
Therefore, they are potential antioxidant products for food and pharmaceutics.
American Psychological Association (APA)
Sriyanti, Ida& Edikresnha, Dhewa& Rahma, Annisa& Munir, Muhammad Miftahul& Rachmawati, Heni& Khairurrijal,. 2017. Correlation between Structures and Antioxidant Activities of PolyvinylpyrrolidoneGarcinia mangostana L. Extract Composite Nanofiber Mats Prepared Using Electrospinning. Journal of Nanomaterials،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1183856
Modern Language Association (MLA)
Sriyanti, Ida…[et al.]. Correlation between Structures and Antioxidant Activities of PolyvinylpyrrolidoneGarcinia mangostana L. Extract Composite Nanofiber Mats Prepared Using Electrospinning. Journal of Nanomaterials No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1183856
American Medical Association (AMA)
Sriyanti, Ida& Edikresnha, Dhewa& Rahma, Annisa& Munir, Muhammad Miftahul& Rachmawati, Heni& Khairurrijal,. Correlation between Structures and Antioxidant Activities of PolyvinylpyrrolidoneGarcinia mangostana L. Extract Composite Nanofiber Mats Prepared Using Electrospinning. Journal of Nanomaterials. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1183856
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183856