Role of Adaptive and Innate Immunity in Type 2 Diabetes Mellitus
Joint Authors
Wang, Guixia
Zhou, Tong
Sun, Lin
Yang, Shuo
Hu, Zheng
Yu, Zhenxiang
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
After the recognition of the essential role of the immune system in the progression of type 2 diabetes mellitus, more studies are focused on the effects produced by the abnormal differentiation of components of the immune system.
In patients suffering from obesity or T2DM, there were alterations in proliferation of T cells and macrophages, and impairment in function of NK cells and B cells, which represented abnormal innate and adaptive immunity.
The abnormality of either innate immunity, adaptive immunity, or both was involved and interacted with each other during the progression of T2DM.
Although previous studies have revealed the functional involvement of T cells in T2DM, and the regulation of metabolism by the innate or adaptive immune system during the pathogenesis of T2DM, there has been a lack of literature reviewing the relevant role of adaptive and innate immunity in the progression of T2DM.
Here, we will review their relevant roles, aiming to provide new thought for the development of immunotherapy in T2DM.
American Psychological Association (APA)
Zhou, Tong& Hu, Zheng& Yang, Shuo& Sun, Lin& Yu, Zhenxiang& Wang, Guixia. 2018. Role of Adaptive and Innate Immunity in Type 2 Diabetes Mellitus. Journal of Diabetes Research،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1183860
Modern Language Association (MLA)
Zhou, Tong…[et al.]. Role of Adaptive and Innate Immunity in Type 2 Diabetes Mellitus. Journal of Diabetes Research No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1183860
American Medical Association (AMA)
Zhou, Tong& Hu, Zheng& Yang, Shuo& Sun, Lin& Yu, Zhenxiang& Wang, Guixia. Role of Adaptive and Innate Immunity in Type 2 Diabetes Mellitus. Journal of Diabetes Research. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1183860
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1183860