Desired Turbulence? Gut-Lung Axis, Immunity, and Lung Cancer
Joint Authors
Vasson, Marie-Paule
Bingula, Rea
Berthon, Jean-Yves
Filaire, Marc
Filaire, Edith
Radosevic-Robin, Nina
Bey, Mathieu
Bernalier-Donadille, Annick
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-17
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
The microbiota includes different microorganisms consisting of bacteria, fungi, viruses, and protozoa distributed over many human body surfaces including the skin, vagina, gut, and airways, with the highest density found in the intestine.
The gut microbiota strongly influences our metabolic, endocrine, and immune systems, as well as both the peripheral and central nervous systems.
Recently, a dialogue between the gut and lung microbiota has been discovered, suggesting that changes in one compartment could impact the other compartment, whether in relation to microbial composition or function.
Further, this bidirectional axis is evidenced in an, either beneficial or malignant, altered immune response in one compartment following changes in the other compartment.
Stimulation of the immune system arises from the microbial cells themselves, but also from their metabolites.
It can be either direct or mediated by stimulated immune cells in one site impacting the other site.
Additionally, this interaction may lead to immunological boost, assisting the innate immune system in its antitumour response.
Thus, this review offers an insight into the composition of these sites, the gut and the lung, their role in shaping the immune system, and, finally, their role in the response to lung cancer.
American Psychological Association (APA)
Bingula, Rea& Filaire, Marc& Radosevic-Robin, Nina& Bey, Mathieu& Berthon, Jean-Yves& Bernalier-Donadille, Annick…[et al.]. 2017. Desired Turbulence? Gut-Lung Axis, Immunity, and Lung Cancer. Journal of Oncology،Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1184188
Modern Language Association (MLA)
Bingula, Rea…[et al.]. Desired Turbulence? Gut-Lung Axis, Immunity, and Lung Cancer. Journal of Oncology No. 2017 (2017), pp.1-15.
https://search.emarefa.net/detail/BIM-1184188
American Medical Association (AMA)
Bingula, Rea& Filaire, Marc& Radosevic-Robin, Nina& Bey, Mathieu& Berthon, Jean-Yves& Bernalier-Donadille, Annick…[et al.]. Desired Turbulence? Gut-Lung Axis, Immunity, and Lung Cancer. Journal of Oncology. 2017. Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1184188
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184188