Implications for Tumor Microenvironment and Epithelial Crosstalk in the Management of Gastrointestinal Cancers
Joint Authors
Ge, Yang
Weygant, Nathaniel
Westphalen, C. Benedikt
Ma, Wen Wee
Vega, Kenneth J.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-31
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Rapid advances in technology are revealing previously unknown organization, cooperation, and limitations within the population of nontumor cells surrounding the tumor epithelium known as the tumor microenvironment (TME).
Nowhere are these findings more pertinent than in the gastrointestinal (GI) tract where exquisite cell specialization supports a complex microenvironmental niche characterized by rapid stemness-associated cell turnover, pathogen sensing, epithelial orchestration of immune signaling, and other facets that maintain the complex balance between homeostasis, inflammation, and disease.
Here, we summarize and discuss select emerging concepts in the precancerous microenvironment, TME, and tumor epithelial-TME crosstalk as well as their implications for the management of GI cancers.
American Psychological Association (APA)
Ge, Yang& Westphalen, C. Benedikt& Ma, Wen Wee& Vega, Kenneth J.& Weygant, Nathaniel. 2019. Implications for Tumor Microenvironment and Epithelial Crosstalk in the Management of Gastrointestinal Cancers. Journal of Oncology،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1184250
Modern Language Association (MLA)
Ge, Yang…[et al.]. Implications for Tumor Microenvironment and Epithelial Crosstalk in the Management of Gastrointestinal Cancers. Journal of Oncology No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1184250
American Medical Association (AMA)
Ge, Yang& Westphalen, C. Benedikt& Ma, Wen Wee& Vega, Kenneth J.& Weygant, Nathaniel. Implications for Tumor Microenvironment and Epithelial Crosstalk in the Management of Gastrointestinal Cancers. Journal of Oncology. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1184250
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184250