Outcome of Surgical Treatment in Late-Onset Capsular Block Syndrome
Joint Authors
Huang, Yang
Ye, Zi
Li, Hang
Li, Zhaohui
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-09
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
To further investigate the pathogenesis of late-onset capsular block syndrome (CBS) and to evaluate the safety of surgical treatment.
Methods.
Seven patients diagnosed with late-onset CBS were retrospectively analyzed.
Anterior chamber depth (ACD), intraocular pressure (IOP), refractive diopter, and best-corrected visual acuity (BCVA) before and after surgery were recorded.
The opaque substance was tested with Western blot, and a flow cytometer multiple array assay system was utilized to evaluate the levels of inflammatory cytokines from opaque substance and aqueous humor, respectively.
Results.
Patients who had undergone surgical treatment showed a significant BCVA and spherical equivalent refractive error improvement (P=0.002, P=0.021, resp.).
Nevertheless, ACD and IOP before and after surgery were in normal range with no difference (P=0.165, P=0.749, resp.).
αB-crystallin and βB-crystallin were detected in all opaque substances.
Tumor necrosis factor-alpha (TNF-α) and interlukin-1β (IL-1β) levels in opaque substance were significantly higher than those in aqueous humor (P=0.038, P=0.007, resp.), while IL-2 and IL-6 were not detected in any samples.
Conclusions.
Opaque substance is derived from human lens epithelial cells.
Inflammatory cytokines may be involved in the pathogenesis of late-onset CBS.
In addition, surgical treatment is an effective approach.
This trial is registered with ChiCTR-IOR-17011287.
American Psychological Association (APA)
Huang, Yang& Ye, Zi& Li, Hang& Li, Zhaohui. 2017. Outcome of Surgical Treatment in Late-Onset Capsular Block Syndrome. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1184566
Modern Language Association (MLA)
Huang, Yang…[et al.]. Outcome of Surgical Treatment in Late-Onset Capsular Block Syndrome. Journal of Ophthalmology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1184566
American Medical Association (AMA)
Huang, Yang& Ye, Zi& Li, Hang& Li, Zhaohui. Outcome of Surgical Treatment in Late-Onset Capsular Block Syndrome. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1184566
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184566