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Autologous Platelet-Rich Plasma Eye Drops for the Treatment of Post-LASIK Chronic Ocular Surface Syndrome
Joint Authors
Alio, Jorge L.
Abdelghany, Ahmed A.
Rodriguez, Alejandra E.
Oliveira, Renan F.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To evaluate the efficacy of autologous platelet-rich plasma (E-PRP) eye drops for the treatment of chronic ocular surface syndrome (OSS) following laser in situ keratomileusis (LASIK).
Methods.
This prospective interventional consecutive clinical study include 156 eyes of 80 patients affected by post-LASIK chronic OSS who were treated with autologous E-PRP 6 times a day as monotherapy for 6 weeks.
Results.
Dry eye symptoms improved in 85% of the cases.
A decrease in at least one quadrant to total disappearance on CFS was observed in 89.6% of the patients who had positive CFS before treatment.
Three eyes presented severe punctate keratitis (1.9%) at baseline, all of which healed completely.
Conjunctival hyperemia improved in 93.3% of the patients with previous signs of ocular surface inflammation.
There was a significant improvement in logMAR CDVA from 0.14 ± 0.19 to 0.06 ± 0.12 (p=0.000), and 74 (71.4%) eyes improved at least 1 line in CDVA.
Conclusion.
Monotherapy with autologous E-PRP is a well-tolerated, safe, and effective treatment for the management of post-LASIK ocular surface syndrome.
Precis.
Monotherapy with autologous platelet-rich plasma eye drops has been shown to be an adequate option for the treatment of post-LASIK chronic ocular surface syndrome.
This trial is registered with NCT03322917.
American Psychological Association (APA)
Alio, Jorge L.& Rodriguez, Alejandra E.& Abdelghany, Ahmed A.& Oliveira, Renan F.. 2017. Autologous Platelet-Rich Plasma Eye Drops for the Treatment of Post-LASIK Chronic Ocular Surface Syndrome. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1184650
Modern Language Association (MLA)
Alio, Jorge L.…[et al.]. Autologous Platelet-Rich Plasma Eye Drops for the Treatment of Post-LASIK Chronic Ocular Surface Syndrome. Journal of Ophthalmology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1184650
American Medical Association (AMA)
Alio, Jorge L.& Rodriguez, Alejandra E.& Abdelghany, Ahmed A.& Oliveira, Renan F.. Autologous Platelet-Rich Plasma Eye Drops for the Treatment of Post-LASIK Chronic Ocular Surface Syndrome. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1184650
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184650