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Advances in the Management of HPV-Related Oropharyngeal Cancer
Joint Authors
Tombolini, V.
Valentini, V.
de Vincentiis, M.
Mezi, S.
Brugnoletti, O.
Polimeni, A.
De Felice, Francesca
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Patients with human papillomavirus- (HPV-) related oropharyngeal squamous cell carcinoma (OPSCC) have a better prognosis than HPV-negative OPSCC when treated with standard high-dose cisplatin-based chemoradiotherapy.
Consistent with this assertion and due to younger age at diagnosis, novel approaches to minimize treatment sequelae while preserving survival outcomes become of paramount importance.
Here, we critically reviewed the evidence-based literature supporting the deintensification strategies in HPV-related OPSCC management, including radiotherapy dose and/or volume reduction, replacement of cisplatin radiosensitising chemotherapy, and the use of transoral surgery.
Undoubtedly, further researches are needed before changing the standard of care in this setting of patients.
American Psychological Association (APA)
De Felice, Francesca& Tombolini, V.& Valentini, V.& de Vincentiis, M.& Mezi, S.& Brugnoletti, O.…[et al.]. 2019. Advances in the Management of HPV-Related Oropharyngeal Cancer. Journal of Oncology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1184670
Modern Language Association (MLA)
De Felice, Francesca…[et al.]. Advances in the Management of HPV-Related Oropharyngeal Cancer. Journal of Oncology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1184670
American Medical Association (AMA)
De Felice, Francesca& Tombolini, V.& Valentini, V.& de Vincentiis, M.& Mezi, S.& Brugnoletti, O.…[et al.]. Advances in the Management of HPV-Related Oropharyngeal Cancer. Journal of Oncology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1184670
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184670