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When Is Evidence Enough Evidence? A Systematic Review and Meta-Analysis of the Trabectome as a Solo Procedure in Patients with Primary Open-Angle Glaucoma
Joint Authors
Hutnik, Cindy
Chow, Jeffrey T. Y.
Solo, Karla
Malvankar-Mehta, Monali S.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The purpose of this systematic review and meta-analysis was to examine the availability of evidence for one of the earliest available minimally invasive glaucoma surgery (MIGS) procedures, the Trabectome.
Various databases were searched up to December 20, 2016, for any published studies assessing the use of the Trabectome as a solo procedure in patients with primary open-angle glaucoma (POAG).
The standardized mean differences (SMD) were calculated for the change in intraocular pressure (IOP) and number of glaucoma mediations used at 1-month, 6-month, and 12-month follow-up.
After screening, three studies and one abstract with analyzable data were included.
The meta-analysis showed statistically significant reductions in IOP and number of glaucoma medications used at all time points.
Though the Trabectome as a solo procedure appears to lower IOP and reduces the number of glaucoma medications, more high-quality studies are required to make definitive conclusions.
The difficulty of obtaining evidence may be one of the many obstacles that limit a full understanding of the potential safety and/or efficacy benefits compared to standard treatments.
The time has come for a thoughtful and integrated approach with stakeholders to determine optimal access to care strategies for our patients.
American Psychological Association (APA)
Chow, Jeffrey T. Y.& Hutnik, Cindy& Solo, Karla& Malvankar-Mehta, Monali S.. 2017. When Is Evidence Enough Evidence? A Systematic Review and Meta-Analysis of the Trabectome as a Solo Procedure in Patients with Primary Open-Angle Glaucoma. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1184704
Modern Language Association (MLA)
Chow, Jeffrey T. Y.…[et al.]. When Is Evidence Enough Evidence? A Systematic Review and Meta-Analysis of the Trabectome as a Solo Procedure in Patients with Primary Open-Angle Glaucoma. Journal of Ophthalmology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1184704
American Medical Association (AMA)
Chow, Jeffrey T. Y.& Hutnik, Cindy& Solo, Karla& Malvankar-Mehta, Monali S.. When Is Evidence Enough Evidence? A Systematic Review and Meta-Analysis of the Trabectome as a Solo Procedure in Patients with Primary Open-Angle Glaucoma. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1184704
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184704