A Systematic Review and Meta-Analysis on Microsurgical Safety and Efficacy of Profunda Artery Perforator Flap in Breast Reconstruction
Joint Authors
Sun, Yang
Qian, Bei
Xiong, Lingyun
Li, Jialun
Sun, Jiaming
Guo, Nengqiang
Wang, Zhenxing
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-29
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Background.
The profunda artery perforator (PAP) flap was first applied in breast reconstruction in 2010 by Robert J.
Allen.
It provided an alternative for autologous breast reconstruction in addition to traditional donor sites.
Currently, literature reporting its microsurgical safety and efficacy is relatively sparse and heterogeneous.
Objective.
To clarify the evidence regarding microsurgical safety and efficacy of PAP flap in breast reconstruction, which may contribute to future surgical decision-making.
Methods.
Multiple databases were systematically searched by two independent reviewers.
The result was statistically analyzed with Meta command of R GUI 3.5.1.
The proportions with 95% confidence intervals (CIs) were calculated by using random-effect model.
Results.
There were 12 studies including 516 PAP flaps meeting the inclusion criteria.
The pooled surgical success rate was 99% (95% CI: 97%–100%) and overall rate of complications was 23% (95% CI: 18%–27%).
The most common individual complication was wound dehiscence with incidence of 6% (95% CI: 4%–9%).
The seroma rate was 2% (95%CI: 0%–6%).
The hematoma rate was 1% (95% CI: 0%–2%).
The partial necrosis rate was 2% (95% CI: 0%–5%).
The rate of total flap loss was 1% (95% CI: 0%–3%).
Conclusion.
To date, this study is the first meta-analysis of microsurgical efficacy and safety evaluation of the PAP flap in breast reconstruction.
This present work confirmed that the PAP flap is safe and reliable in breast reconstruction with high success rate, but a relatively low complication rate.
Moreover, it might be more than an alternative to the deep inferior epigastric perforator flap (DIEP) in microsurgical breast reconstruction in selected patients.
American Psychological Association (APA)
Qian, Bei& Xiong, Lingyun& Li, Jialun& Sun, Yang& Sun, Jiaming& Guo, Nengqiang…[et al.]. 2019. A Systematic Review and Meta-Analysis on Microsurgical Safety and Efficacy of Profunda Artery Perforator Flap in Breast Reconstruction. Journal of Oncology،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1184729
Modern Language Association (MLA)
Qian, Bei…[et al.]. A Systematic Review and Meta-Analysis on Microsurgical Safety and Efficacy of Profunda Artery Perforator Flap in Breast Reconstruction. Journal of Oncology No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1184729
American Medical Association (AMA)
Qian, Bei& Xiong, Lingyun& Li, Jialun& Sun, Yang& Sun, Jiaming& Guo, Nengqiang…[et al.]. A Systematic Review and Meta-Analysis on Microsurgical Safety and Efficacy of Profunda Artery Perforator Flap in Breast Reconstruction. Journal of Oncology. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1184729
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184729