Optic Neuritis in the Older Chinese Population: A 5-Year Follow-Up Study
Joint Authors
Zhou, Huanfen
Xu, Quangang
Peng, Chunxia
Wang, Junqing
Qin, Limin
Zhao, Jie
Teng, Da
Lin, Dahe
Ai, Nanping
Wei, Shihui
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-11
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
This study aims to describe the clinical manifestations and outcomes in a cohort of older Chinese patients.
Method.
A retrospective study of patients aged ≥ 45 years who had a first episode of optic neuritis (ON) between May 2008 and November 2012.
Clinical features at onset and last follow-up were analyzed within subgroups (age 45–65 years and age ≥ 65 years).
Results.
76 patients (99 eyes) were included, of which 58% were females.
The mean age at presentation was 55.53 ± 8.29 years (range: 45–83 years).
Vision loss was severe at presentation, with initial best corrected vision activity (BCVA) < 20/200 in 93% and final BCVA < 20/200 in 53% of patients at 5-year follow-up.
Final BCVA significantly correlated with the initial BCVA and peripapillary retinal nerve fiber layer.
At last follow-up, 14.5% were diagnosed with neuromyelitis optica spectrum disorder (NMOSD), 1.3% were diagnosed with multiple sclerosis (MS), 5.2% with chronic relapsing inflammatory optic neuropathy, 1.3% with infectious ON, and 19.7% with autoimmune ON.
None of the elderly group (≥65 years) developed NMOSD or MS.
Conclusion.
Chinese patients in the age group ≥ 65 years with ON are less likely to develop NMOSD or MS.
Notwithstanding, they had more severe visual loss at onset and poor recovery.
American Psychological Association (APA)
Wang, Junqing& Zhou, Huanfen& Qin, Limin& Peng, Chunxia& Zhao, Jie& Teng, Da…[et al.]. 2017. Optic Neuritis in the Older Chinese Population: A 5-Year Follow-Up Study. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1184776
Modern Language Association (MLA)
Wang, Junqing…[et al.]. Optic Neuritis in the Older Chinese Population: A 5-Year Follow-Up Study. Journal of Ophthalmology No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1184776
American Medical Association (AMA)
Wang, Junqing& Zhou, Huanfen& Qin, Limin& Peng, Chunxia& Zhao, Jie& Teng, Da…[et al.]. Optic Neuritis in the Older Chinese Population: A 5-Year Follow-Up Study. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1184776
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184776