The Combination of Ketorolac with Local Anesthesia for Pain Control in Day Care Retinal Detachment Surgery: A Randomized Controlled Trial
Joint Authors
Lu, Lin
Zhao, Xiujuan
Li, Tao
Chen, Xiaohong
Liu, Bingqian
Liang, Xiaoling
Li, Jiaqing
Li, Yonghao
Yu, Xiling
Lyu, Cancan
Tanumiharjo, Silvia
Jin, Chenjin
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-09
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
This study aims to evaluate the efficacy of ketorolac with local anesthesia compared to local anesthesia alone for perioperative pain control in day care retinal detachment surgery.
The randomized controlled trial included 59 eyes of 59 participants for retinal detachment surgery who were randomly assigned (1 : 1) into the ketorolac (K) group and control (C) group.
All participants underwent conventional local anesthesia while patients in the K group received an extra administration of preoperative ketorolac.
Participants in the K group had a statistically significantly lower intraoperative NRS score (median 1.0 versus 3.0, P=0.003), lower postoperative NRS score (median 0 versus 1.0, P=0.035), fewer proportion of rescue analgesic requirement (10% versus 34.5%, P=0.023), and lower incidence of postoperative nausea and vomiting (13.3% versus 41.4%, P=0.015) compared to the C group.
Intraocular pressure (IOP) changes (△IOP) were significantly reduced in the K group (median 1.9 versus 3.0, P=0.038) compared to the C group 24 hours postoperatively.
In conclusion, the combination of local anesthesia with ketorolac provides better pain control in retinal detachment surgery compared to local anesthesia alone.
The beneficial effect of ketorolac with local anesthesia may contribute to a wider-spread adoption of day care retinal detachment surgery.
This trial is registered with ClinicalTrials.gov NCT02729285.
American Psychological Association (APA)
Chen, Xiaohong& Liu, Bingqian& Liang, Xiaoling& Li, Jiaqing& Li, Tao& Li, Yonghao…[et al.]. 2017. The Combination of Ketorolac with Local Anesthesia for Pain Control in Day Care Retinal Detachment Surgery: A Randomized Controlled Trial. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1184779
Modern Language Association (MLA)
Chen, Xiaohong…[et al.]. The Combination of Ketorolac with Local Anesthesia for Pain Control in Day Care Retinal Detachment Surgery: A Randomized Controlled Trial. Journal of Ophthalmology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1184779
American Medical Association (AMA)
Chen, Xiaohong& Liu, Bingqian& Liang, Xiaoling& Li, Jiaqing& Li, Tao& Li, Yonghao…[et al.]. The Combination of Ketorolac with Local Anesthesia for Pain Control in Day Care Retinal Detachment Surgery: A Randomized Controlled Trial. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1184779
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184779