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Effect of Topical Nepafenac on Central Foveal Thickness following Panretinal Photocoagulation in Diabetic Patients
Joint Authors
Ghalwash, D.
Abu Hussein, Nahla B.
Abdel-Kader, Ahmed A.
Mohalhal, Ahmed A.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-27
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To evaluate effectiveness of topical nepafenac in reducing macular edema following panretinal photocoagulation (PRP).
Design.
Prospective randomized double-blinded controlled study.
Methods.
Sixty eyes of 60 patients having proliferative or severe nonproliferative diabetic retinopathy had PRP.
Patients were then divided into two groups: nepafenac group (30 eyes) receiving 1% topical nepafenac eye drops for 6 months and control group (30 eyes) receiving carboxymethylcellulose eye drops for 6 months.
Best-corrected visual acuity (BCVA) and macular optical coherence tomography were followed up at 1, 2, 4, and 6 months after PRP.
Results.
BCVA was significantly better in nepafenac group than in control group at all follow-ups (P<0.01).
At 6 months post-PRP, logMAR BCVA was 0.11 ± 0.04 (equivalent to 20/26 Snellen acuity) in the nepafenac group and 0.18 ± 0.08 (equivalent to 20/30 Snellen acuity) in the control group (P<0.01).
Central foveal thickness (CFT) increased in both groups from the first month after PRP.
Increase in CFT was higher in control group than in nepafenac group throughout follow-up, but the difference became statistically significant only after 4 months.
No significant ocular adverse events were reported with topical nepafenac.
Conclusion.
Topical nepafenac can minimize macular edema and stabilize visual acuity following PRP for diabetic patients.
American Psychological Association (APA)
Abu Hussein, Nahla B.& Mohalhal, Ahmed A.& Ghalwash, D.& Abdel-Kader, Ahmed A.. 2017. Effect of Topical Nepafenac on Central Foveal Thickness following Panretinal Photocoagulation in Diabetic Patients. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1184842
Modern Language Association (MLA)
Abu Hussein, Nahla B.…[et al.]. Effect of Topical Nepafenac on Central Foveal Thickness following Panretinal Photocoagulation in Diabetic Patients. Journal of Ophthalmology No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1184842
American Medical Association (AMA)
Abu Hussein, Nahla B.& Mohalhal, Ahmed A.& Ghalwash, D.& Abdel-Kader, Ahmed A.. Effect of Topical Nepafenac on Central Foveal Thickness following Panretinal Photocoagulation in Diabetic Patients. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1184842
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184842