Association between Asymptomatic Unilateral Internal Carotid Artery Stenosis and Electrophysiological Function of the Retina and Optic Nerve
Joint Authors
Safranow, Krzysztof
Machalinska, Anna
Machalinski, Boguslaw
Kawa, Miłosz P.
Lubiński, Wojciech
Kowalska-Budek, Aleksandra
Kazimierczak, Arkadiusz
Kirkiewicz, Marta
Wilk, Grażyna
Gutowski, Piotr
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-12
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Purpose.
This study was designed to assess retinal and optic nerve bioelectrical function in patients with unilateral asymptomatic but hemodynamically significant internal carotid artery stenosis (ICAS).
Methods.
Forty-two subjects with a diagnosis of unilateral ICAS and 34 controls were analyzed.
Full-field electroretinogram (ERG), pattern electroretinogram (PERG), and pattern visual-evoked potentials, as well as optical coherence tomography and ophthalmological examination, were performed.
Data analysis included eyes ipsilateral to ICAS (EIS) and eyes contralateral to ICAS (ECS).
Results.
Intraocular pressure was significantly decreased in EIS and ECS compared to that in the controls.
In the macula, both the cube average thickness and cube volume values were significantly reduced both in EIS and ECS compared to those in the controls.
Similarly, PERG P50 and N95 wave amplitudes were significantly smaller in EIS and ECS compared to those in the controls.
The ERG rod b-wave and rod-cone a-wave amplitudes were decreased, and implicit times were significantly prolonged, whereas the OP wave index was reduced in EIS compared to that in the controls.
No differences in IOP, OCT, or ERG and PERG parameters were identified between EIS and ECS.
Conclusions.
Our study demonstrated that retinal bioelectrical function is negatively affected by ICAS despite the absence of objective clinical signs and symptoms of ocular ischemia.
American Psychological Association (APA)
Machalinska, Anna& Kowalska-Budek, Aleksandra& Kawa, Miłosz P.& Kazimierczak, Arkadiusz& Safranow, Krzysztof& Kirkiewicz, Marta…[et al.]. 2017. Association between Asymptomatic Unilateral Internal Carotid Artery Stenosis and Electrophysiological Function of the Retina and Optic Nerve. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1184908
Modern Language Association (MLA)
Machalinska, Anna…[et al.]. Association between Asymptomatic Unilateral Internal Carotid Artery Stenosis and Electrophysiological Function of the Retina and Optic Nerve. Journal of Ophthalmology No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1184908
American Medical Association (AMA)
Machalinska, Anna& Kowalska-Budek, Aleksandra& Kawa, Miłosz P.& Kazimierczak, Arkadiusz& Safranow, Krzysztof& Kirkiewicz, Marta…[et al.]. Association between Asymptomatic Unilateral Internal Carotid Artery Stenosis and Electrophysiological Function of the Retina and Optic Nerve. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1184908
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184908