![](/images/graphics-bg.png)
Evaluation of Predictive Factors for Successful Intravitreal Dexamethasone in Pseudophakic Cystoid Macular Edema
Joint Authors
Dick, H. Burkhard
Kakkassery, Vinodh
Schultz, Tim
Wunderlich, Marc Ilan
Schargus, Marc
Rehrmann, Jörg
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-19
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Purpose.
To determine the efficacy, safety, and predictive outcome factors for intravitreal dexamethasone implant (DEX) in pseudophakic cystoid macular edema (PCME).
Methods.
Retrospective, interventional, controlled study.
Patients included had to have clinically significant PCME and have been treated with the DEX between 2012 and 2015.
Charts and one-year data were selected consecutively, and efficacy and safety were abstracted.
Visual acuity (VA) and central foveal thickness (CFT) were analysed.
Results.
Nineteen patient data sets were analysed.
After treatment with DEX, mean VA increased significantly by 0.2 logMAR (p=0.034), while the mean CFT was reduced significantly by 162.79 μm (p<0.001).
Five patients receiving a combination of DEX/bevacizumab have not experienced a higher mean VA gain or CFT reduction compared to fourteen patients receiving DEX alone.
Decision rules, when to combine DEX with bevacizumab, have not been defined before the study.
Only posttreatment VA gains in the nonhypertensive subgroup (n=11) were significantly better (p=0.026).
Analysis of data from diabetes patients (n=4) versus nondiabetics yielded no significant differences in efficacy.
There have been no adverse events within follow-up time.
Conclusion.
The use of DEX in PCME showed significant improvements in VA and CFT.
The VA seems to show greater improvements in patients without hypertension.
American Psychological Association (APA)
Kakkassery, Vinodh& Schultz, Tim& Wunderlich, Marc Ilan& Schargus, Marc& Dick, H. Burkhard& Rehrmann, Jörg. 2017. Evaluation of Predictive Factors for Successful Intravitreal Dexamethasone in Pseudophakic Cystoid Macular Edema. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1184977
Modern Language Association (MLA)
Kakkassery, Vinodh…[et al.]. Evaluation of Predictive Factors for Successful Intravitreal Dexamethasone in Pseudophakic Cystoid Macular Edema. Journal of Ophthalmology No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1184977
American Medical Association (AMA)
Kakkassery, Vinodh& Schultz, Tim& Wunderlich, Marc Ilan& Schargus, Marc& Dick, H. Burkhard& Rehrmann, Jörg. Evaluation of Predictive Factors for Successful Intravitreal Dexamethasone in Pseudophakic Cystoid Macular Edema. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1184977
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184977