Antihyperglycemic, Vasodilator, and Diuretic Activities of Microencapsulated Bioactive Product from Moringa stenopetala Leaves Extract
Joint Authors
Teka, Frehiwot
Sileshi, Meron
Abebe, Abiy
Emire, Shimelis Admassu
Dadi, Debebe Worku
Hagos, Asfaw Debella
Woldekidan, Samuel
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-14
Country of Publication
Egypt
No. of Pages
8
Abstract EN
Moringa stenopetala has nutritional and medicinal values, which is widely used by the local communities.
The study aimed to evaluate the antihyperglycemic, vasodilator, and diuretic activities of the microencapsulated bioactive product from M.
stenopetala leaves extract.
Microencapsulation of the extract was done by spray drying technique using maltodextrin and pectin as coating materials with the core: coating ratio of 1 : 6.
Then, the antihyperglycemic, diuretic, and vasodilator activities were evaluated after the product was administered to experimental animals at different doses and compared with the control groups.
There were no observed physical, behavioral, and physiological changes on the mice during the acute toxicity test.
The results also indicated no toxicity signs and death occurrence in the experimental animals up to 5000 mg/kg administered dose.
Therefore, microencapsulated M.
stenopetala leaves extract does not produce adverse effects in experimental mice.
The study also showed that the microencapsulated bioactive product exhibited significant antihyperglycemic, vasodilator, and diuretic activities as the doses increase.
Therefore, the study showed that microencapsulated bioactive product has significant medicinal values.
Further detailed studies are recommended on chronic toxicity tests and to understand the possible mechanism of actions on the antihyperglycemic, vasodilator, and diuretic activities of the microencapsulated product.
American Psychological Association (APA)
Dadi, Debebe Worku& Emire, Shimelis Admassu& Hagos, Asfaw Debella& Teka, Frehiwot& Woldekidan, Samuel& Abebe, Abiy…[et al.]. 2020. Antihyperglycemic, Vasodilator, and Diuretic Activities of Microencapsulated Bioactive Product from Moringa stenopetala Leaves Extract. Journal of Food Quality،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1184988
Modern Language Association (MLA)
Dadi, Debebe Worku…[et al.]. Antihyperglycemic, Vasodilator, and Diuretic Activities of Microencapsulated Bioactive Product from Moringa stenopetala Leaves Extract. Journal of Food Quality No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1184988
American Medical Association (AMA)
Dadi, Debebe Worku& Emire, Shimelis Admassu& Hagos, Asfaw Debella& Teka, Frehiwot& Woldekidan, Samuel& Abebe, Abiy…[et al.]. Antihyperglycemic, Vasodilator, and Diuretic Activities of Microencapsulated Bioactive Product from Moringa stenopetala Leaves Extract. Journal of Food Quality. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1184988
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1184988