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Thinner Corneas Appear to Have More Striking Effects of Corneal Collagen Crosslinking in Patients with Progressive Keratoconus
Joint Authors
Xu, Yan-yun
Mu, Guo-ying
Han, Yunfei
Zhu, Wei
Liu, Yuling
Liu, Zhen
Dou, Xiaoxiao
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
To analyze the outcomes and difference after UVA/riboflavin corneal collagen crosslinking (CXL) in four different corneal thickness groups of patients with progressive keratoconus.
Methods.
Retrospective study.
Eyes with progressive keratoconus after CXL were divided into 4 subgroups as follows: group 1, thinnest corneal thickness (TCT) ≤ 400 µm; group 2, 400 µm < TCT ≤ 450 µm; group 3, 450 µm < TCT ≤ 500 µm; group 4, TCT ≥ 500 µm.
Baseline, 6-month, and 12-month visual acuity, corneal topography, TCT, and endothelial cell density were evaluated.
Results.
The analysis included 123 eyes of 101 patients.
At 6 and 12 months after CXL, there was a mean improvement about visual acuity and keratometry values in all patients.
There was a reduction in the change of maximum keratometry (Kmax) with the increase of TCT.
After 1 year of treatment, it was 3.04 ± 0.75 D in group 1, 2.38 ± 0.51 D in group 2, 1.57 ± 0.35 D in group 3, and 0.31 ± 0.20 D in group 4.
Conclusion.
CXL is successful in halting the progression of keratoconus and there was a negative linear correlation between TCT and Kmax.
Advanced cases of progressive keratoconus seemed to obtain more benefits from the flatting effects of CXL.
American Psychological Association (APA)
Han, Yunfei& Xu, Yan-yun& Zhu, Wei& Liu, Yuling& Liu, Zhen& Dou, Xiaoxiao…[et al.]. 2017. Thinner Corneas Appear to Have More Striking Effects of Corneal Collagen Crosslinking in Patients with Progressive Keratoconus. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1185174
Modern Language Association (MLA)
Han, Yunfei…[et al.]. Thinner Corneas Appear to Have More Striking Effects of Corneal Collagen Crosslinking in Patients with Progressive Keratoconus. Journal of Ophthalmology No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1185174
American Medical Association (AMA)
Han, Yunfei& Xu, Yan-yun& Zhu, Wei& Liu, Yuling& Liu, Zhen& Dou, Xiaoxiao…[et al.]. Thinner Corneas Appear to Have More Striking Effects of Corneal Collagen Crosslinking in Patients with Progressive Keratoconus. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1185174
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185174