Changes in Retinal and Choroidal Vascular Blood Flow after Oral Sildenafil: An Optical Coherence Tomography Angiography Study
Joint Authors
Salcedo-Villanueva, Guillermo
Velez-Montoya, Raul
Berrones, David
Morales-Cantón, Virgilio
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-09
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To describe changes in the retina and choroidal flow by optical coherence tomography angiography (OCT-A) after a single dose of oral sildenafil.
Method.
A case-control study.
Patients in the study group received 50 mg of oral sildenafil.
Patients in the control group received a sham pill.
Retinal and choroidal images were obtained at baseline (before pill ingestion) and 1 hour after ingestion.
Central macular and choroidal thickness, choroidal and outer retina flow, and the retinal and choroidal vascular density were compared using a Mann-Whitney U test.
Results.
Twenty eyes were enrolled into the study group and 10 eyes in the control group.
There was a significant difference in central choroidal thickness and outer retina blood flow between groups after 1 hour of sildenafil ingestion (p<0.01).
There were no differences in central macular thickness, choroidal flow, and retinal vascular density among groups.
Conclusions.
A single dose of oral sildenafil increases choroidal thickness, probably due to sildenafil-induced vasodilation.
American Psychological Association (APA)
Berrones, David& Salcedo-Villanueva, Guillermo& Morales-Cantón, Virgilio& Velez-Montoya, Raul. 2017. Changes in Retinal and Choroidal Vascular Blood Flow after Oral Sildenafil: An Optical Coherence Tomography Angiography Study. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1185290
Modern Language Association (MLA)
Berrones, David…[et al.]. Changes in Retinal and Choroidal Vascular Blood Flow after Oral Sildenafil: An Optical Coherence Tomography Angiography Study. Journal of Ophthalmology No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1185290
American Medical Association (AMA)
Berrones, David& Salcedo-Villanueva, Guillermo& Morales-Cantón, Virgilio& Velez-Montoya, Raul. Changes in Retinal and Choroidal Vascular Blood Flow after Oral Sildenafil: An Optical Coherence Tomography Angiography Study. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1185290
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185290