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Preoperative Intravitreal Conbercept Facilitates Vitrectomy in Proliferative Diabetic Retinopathy: Is Attention Required for the Fellow Eye?
Joint Authors
Xu, Guoxing
Xu, Wei
Cheng, Weijing
Yao, Yao
Guo, Jian
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To evaluate the effect of preoperative intravitreal conbercept (IVC) injection on patients with proliferative diabetic retinopathy (PDR).
Methods.
Medical records of patients who underwent vitrectomy due to complications of PDR were retrospectively reviewed.
Patients were grouped as the IVC group and non-IVC group according to preoperative IVC.
Preoperative, intraoperative, and postoperative data of both eyes were collected.
The main outcome measures were best-corrected visual acuity (BCVA), intraocular pressure (IOP), central retinal thickness (CRT), and incidence of tractional retinal detachment (TRD).
Results.
A total of 37 cases were included, 16 in the IVC group and 21 in the non-IVC group.
Preoperative IVC significantly reduced surgical duration (IVC vs.
non-IVC, 88.9 ± 11.9 min vs.
97.8 ± 12.8 min, p < 0.05).
In the vitrectomized eye, no significant difference existed between the IVC group and non-IVC group regarding postoperative BCVA (logMAR, 1.20 ± 0.53 vs.
1.27 ± 0.54, p = 0.68), IOP (16.5 ± 2.9 mmHg vs.
15.6 ± 3.7 mmHg, p = 0.44), and CRT (330.1 ± 35.2 μm vs.
319.2 ± 32.5 μm, p=0.34).
In the fellow eye, 6 cases in the IVC group were diagnosed with TRD during postoperative follow-up, while only 2 cases were diagnosed in the non-IVC group (p < 0.05).
Conclusion.
Preoperative intravitreal injection of conbercept has effectively facilitated vitrectomy in PDR patients, but it potentially promotes tractional retinal detachment in the fellow eye following preoperative injection.
American Psychological Association (APA)
Xu, Wei& Cheng, Weijing& Yao, Yao& Guo, Jian& Xu, Guoxing. 2019. Preoperative Intravitreal Conbercept Facilitates Vitrectomy in Proliferative Diabetic Retinopathy: Is Attention Required for the Fellow Eye?. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1185327
Modern Language Association (MLA)
Xu, Wei…[et al.]. Preoperative Intravitreal Conbercept Facilitates Vitrectomy in Proliferative Diabetic Retinopathy: Is Attention Required for the Fellow Eye?. Journal of Ophthalmology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1185327
American Medical Association (AMA)
Xu, Wei& Cheng, Weijing& Yao, Yao& Guo, Jian& Xu, Guoxing. Preoperative Intravitreal Conbercept Facilitates Vitrectomy in Proliferative Diabetic Retinopathy: Is Attention Required for the Fellow Eye?. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1185327
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185327