In Vivo Confocal Microscopy of Cornea in Patients with Terrien’s Marginal Corneal Degeneration
Joint Authors
Chen, Ting
Li, Qiangxiang
Tang, Xiangbo
Liao, Min
Wang, Hua
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
This study was aimed at observing the morphological changes of the cornea with ocular in vivo confocal microscopy (IVCM) in patients with Terrien’s marginal degeneration (TMD).
Ten patients (20 eyes) with TMD treated in the Department of Ophthalmology, Xiangya Hospital, and 10 healthy controls (20 eyes) were included in the current study.
A detailed slit lamp microscopy, anterior segment photography, and corneal IVCM examination were performed for each eye.
The density of central and marginal corneal epithelial cells, stromal cells, and subepithelial nerve fibers was compared between the two groups using the Wilcoxon rank sum test.
Compared with the control group, the corneal epithelial and endothelial cells in the TMD group showed granular highly reflective substances and thinner subepithelial nerve fibers.
The uneven dot-like highly reflective substances without cell structures appeared in the stromal layer of the cornea.
The density of central and marginal corneal epithelial cells, stromal cells, and subepithelial nerve fibers was lower in the TMD group (p<0.05), and they were negatively correlated with severity of the disease (p<0.05).
Our study demonstrated that the density of corneal epithelial cells, stromal cells, and sensory plexus nerve fibers was significantly reduced in the TMD group.
The pathological changes were more obvious in the marginal cornea, and it is correlated with severity of the disease.
American Psychological Association (APA)
Chen, Ting& Li, Qiangxiang& Tang, Xiangbo& Liao, Min& Wang, Hua. 2019. In Vivo Confocal Microscopy of Cornea in Patients with Terrien’s Marginal Corneal Degeneration. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1185391
Modern Language Association (MLA)
Chen, Ting…[et al.]. In Vivo Confocal Microscopy of Cornea in Patients with Terrien’s Marginal Corneal Degeneration. Journal of Ophthalmology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1185391
American Medical Association (AMA)
Chen, Ting& Li, Qiangxiang& Tang, Xiangbo& Liao, Min& Wang, Hua. In Vivo Confocal Microscopy of Cornea in Patients with Terrien’s Marginal Corneal Degeneration. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1185391
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185391