Perspectives of Autologous Mesenchymal Stem-Cell Transplantation in Macular Hole Surgery: A Review of Current Findings
Joint Authors
Nuzzi, Raffaele
Tridico, Federico
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The main treatment available for idiopathic macular holes is represented by pars plana vitrectomy with internal limiting membrane peeling.
However, late-stage macular holes are affected by a higher risk of surgical failure.
Although adjuvant techniques can be employed, a satisfactory functional recovery is difficult to achieve in refractory macular holes.
Given their neuroprotective and antiapoptotic properties, mesenchymal stem cells (MSCs) may represent an appealing approach to treat these extreme cases.
The purpose of this review is to highlight the findings regarding healing mechanisms exerted by mesenchymal stem cells and preliminary application in cases of refractory macular holes.
When compared with MSCs, MSC-derived exosomes may represent a feasible alternative, given their reduced risk of undesired proliferation and easiness of use.
American Psychological Association (APA)
Nuzzi, Raffaele& Tridico, Federico. 2019. Perspectives of Autologous Mesenchymal Stem-Cell Transplantation in Macular Hole Surgery: A Review of Current Findings. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1185397
Modern Language Association (MLA)
Nuzzi, Raffaele& Tridico, Federico. Perspectives of Autologous Mesenchymal Stem-Cell Transplantation in Macular Hole Surgery: A Review of Current Findings. Journal of Ophthalmology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1185397
American Medical Association (AMA)
Nuzzi, Raffaele& Tridico, Federico. Perspectives of Autologous Mesenchymal Stem-Cell Transplantation in Macular Hole Surgery: A Review of Current Findings. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1185397
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185397