Structural and Biomechanical Corneal Differences between Type 2 Diabetic and Nondiabetic Patients
Joint Authors
Falcão-Reis, Fernando M.
Falcão, Manuel
Beato, João
Esteves Leandro, João
Reis, David
Rosas, Vítor
Carneiro, Ângela M.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Purpose.
To analyze and compare corneal structural and biomechanical properties, characterized by corneal hysteresis (CH) and resistance factor (CRF), between patients with and without type 2 diabetes mellitus (DM), and determine the main ocular variables that influence them.
Methods.
Sixty diabetic and 48 age- and sex-matched non-DM patients were enrolled in this cross-sectional study.
The DM group was analyzed according to DM duration ( CH and CRF were evaluated using the Ocular Response Analyzer® (ORA). Central corneal thickness (CCT) was determined by Scheimpflug tomography (Pentacam® HR). Intraocular pressure was obtained with ORA (IOPcc) and Goldmann applanation tonometry (IOP-GAT). Univariate and multivariate linear regression analyses were performed to evaluate the relationship between demographical, clinical, and ocular variables with the biomechanical properties. Results. There were no statistically significant differences in the CH and the CRF between DM and non-DM groups (p=0.637 and p=0.439, respectively). Also, there was no statistical difference between groups for the CCT, IOPcc, or IOP-GAT. Multivariate linear regression analysis showed that CH was positively associated with CCT (p<0.001) and negatively associated with IOPcc (p<0.001), while CRF was positively associated with CCT (p<0.001) and IOPcc (p=0.014). Conclusion. The CCT and IOPcc were found to be the main parameters that affect corneal biomechanical properties both in diabetics and controls. In this study, there was no significant effect of DM type 2 on corneal biomechanics.
American Psychological Association (APA)
Beato, João& Esteves Leandro, João& Reis, David& Falcão, Manuel& Rosas, Vítor& Carneiro, Ângela M.…[et al.]. 2019. Structural and Biomechanical Corneal Differences between Type 2 Diabetic and Nondiabetic Patients. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1185488
Modern Language Association (MLA)
Beato, João…[et al.]. Structural and Biomechanical Corneal Differences between Type 2 Diabetic and Nondiabetic Patients. Journal of Ophthalmology No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1185488
American Medical Association (AMA)
Beato, João& Esteves Leandro, João& Reis, David& Falcão, Manuel& Rosas, Vítor& Carneiro, Ângela M.…[et al.]. Structural and Biomechanical Corneal Differences between Type 2 Diabetic and Nondiabetic Patients. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1185488
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185488