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Corneal Backscatters as an Objective Index for Assessing Fuchs’ Endothelial Corneal Dystrophy: A Pilot Study
Joint Authors
Hsiao, Ching-Hsi
Chen, Phil Y. F.
Ma, David H. K.
Tan, Hsin-Yuan
Chu, Hsueh-Yen
Chang, Chee-Jen
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-02
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
To provide an objective, quantitative approach for monitoring Fuchs’ endothelial corneal dystrophy (FECD), with Scheimpflug imaging.
Design.
This is a retrospective case-control pilot study.
Methods.
The study group consisted of 53 eyes in 27 patients diagnosed with FECD, with normal subjects paired as control.
Main outcome measures were corneal thickness, morphological patterns on densitograms, and indices of corneal density including the average area density (mean AD) and the average ratio of Descemet’s membrane density versus area density (DM/AD) in Pentacam Scheimpflug images.
Results.
There were no significant differences in age and corneal thickness between FECD and normal groups.
Morphologically, hanging-hammock patterns were noted on the densitograms of FECD patients, which were different from the high-back chair patterns in normal subjects.
Quantitatively, mean AD and DM/AD were both elevated in FECD patients as compared with normal subjects (P=0.01 and 0.025, resp.).
In addition, FECD patients with corneal edema had significantly higher mean AD (P=0.018) than those without corneal edema.
Conclusions.
This pilot study shows that Pentacam system provides an objective, quantitative way to approach FECD corneas.
It can assist ophthalmologists in detecting the early change and in monitoring disease progression of FECD.
Further studies are needed to consolidate the findings.
American Psychological Association (APA)
Chu, Hsueh-Yen& Hsiao, Ching-Hsi& Chen, Phil Y. F.& Ma, David H. K.& Chang, Chee-Jen& Tan, Hsin-Yuan. 2017. Corneal Backscatters as an Objective Index for Assessing Fuchs’ Endothelial Corneal Dystrophy: A Pilot Study. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1185568
Modern Language Association (MLA)
Chu, Hsueh-Yen…[et al.]. Corneal Backscatters as an Objective Index for Assessing Fuchs’ Endothelial Corneal Dystrophy: A Pilot Study. Journal of Ophthalmology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1185568
American Medical Association (AMA)
Chu, Hsueh-Yen& Hsiao, Ching-Hsi& Chen, Phil Y. F.& Ma, David H. K.& Chang, Chee-Jen& Tan, Hsin-Yuan. Corneal Backscatters as an Objective Index for Assessing Fuchs’ Endothelial Corneal Dystrophy: A Pilot Study. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1185568
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185568