Bruch’s Membrane Opening Minimum Rim Width Measurement with SD-OCT: A Method to Correct for the Opening Size of Bruch’s Membrane
Joint Authors
Kromer, Robert
Spitzer, Martin Stephan
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-02
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
A precise evaluation of the retinal nerve fiber layer thickness (RNFLT) is key for diagnosing and monitoring glaucoma.
The Bruch’s membrane opening minimum rim width (BMO-MRW) has been proposed as a reproducible assessment of the optic nerve.
The BMO-MRW measures the minimum distance from the BMO to the internal limiting membrane.
We propose an approach to correct the BMO-MRW using the BMO size for increased accuracy in interindividual comparisons in future studies.
Eighty-one healthy patients received SPECTRALIS spectral domain optical coherence tomography measurements for the peripapillary RNFLT and BMO-MRW.
We calculated a BMO size-corrected BMO-MRW using the mean BMO size of our cohort.
BMO size was defined using the manufacturer-provided BMO area and manually measured BMO perimeter.
We observed that the BMO-MRW correlated highly with the perimeter (r=−0.553, p<0.0001) and the area of the BMO (r=−0.546, p<0.0001).
Using these parameters, we provided a corrected BMO size-adjusted BMO-MRW which was better correlated with the RNFLT compared to the noncorrected one (z=−3.3495, p=0.0004).
We demonstrated the dependency of the BMO-MRW on ONH size.
Furthermore, we showed the superiority of the corrected BMO-MRW using either the manually measured optic nerve head perimeter or the automatically provided ONH for future studies.
American Psychological Association (APA)
Kromer, Robert& Spitzer, Martin Stephan. 2017. Bruch’s Membrane Opening Minimum Rim Width Measurement with SD-OCT: A Method to Correct for the Opening Size of Bruch’s Membrane. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1185585
Modern Language Association (MLA)
Kromer, Robert& Spitzer, Martin Stephan. Bruch’s Membrane Opening Minimum Rim Width Measurement with SD-OCT: A Method to Correct for the Opening Size of Bruch’s Membrane. Journal of Ophthalmology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1185585
American Medical Association (AMA)
Kromer, Robert& Spitzer, Martin Stephan. Bruch’s Membrane Opening Minimum Rim Width Measurement with SD-OCT: A Method to Correct for the Opening Size of Bruch’s Membrane. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1185585
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185585