The Association between Adiposity and the Risk of Glaucoma: A Meta-Analysis
Joint Authors
Liu, Weiming
Ling, Jiawen
Chen, Yiyi
Wu, Yan
Lu, Pei-Rong
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-12
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Purpose.
This meta-analysis was conducted to determine the potential association between adiposity and glaucoma incidence.
Materials and Methods.
A comprehensive literature search was performed in PubMed and ISI Web of Science.
A meta-analysis was conducted using STATA software.
Results.
Fifteen eligible studies involving 2,445,980 individuals were included to investigate the association between adiposity and glaucoma incidence.
The relative risks (RRs) were pooled with 95% confidence intervals (CI) by using a random-effects model.
The pooled RR between adiposity and elevated intraocular pressure (IOP) was 1.73 (95% CI, 1.18–2.54), whereas that between adiposity and open-angle glaucoma (OAG) was 0.97 (95% CI, 0.83–1.13).
The pooled RR between abdominal adiposity and glaucoma was 1.28 (95% CI, 1.15–1.41), whereas that between general adiposity and glaucoma was 1.09 (95% CI, 0.87–1.37).
Results of subgroup analysis by sex indicated the association between adiposity and glaucoma in the female group (RR, 1.31; 95% CI, 1.05–1.64), but not in the male group (RR, 1.11; 95% CI, 0.77–1.60).
The pooled RR of cohort studies and cross-sectional studies were 1.00 (95% CI, 0.84–1.20) and 1.22 (95% CI, 0.89–1.66), respectively.
Conclusions.
Adiposity has a higher risk of elevated IOP, and abdominal adiposity has a positive association with glaucoma, especially in female patients.
American Psychological Association (APA)
Liu, Weiming& Ling, Jiawen& Chen, Yiyi& Wu, Yan& Lu, Pei-Rong. 2017. The Association between Adiposity and the Risk of Glaucoma: A Meta-Analysis. Journal of Ophthalmology،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1185830
Modern Language Association (MLA)
Liu, Weiming…[et al.]. The Association between Adiposity and the Risk of Glaucoma: A Meta-Analysis. Journal of Ophthalmology No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1185830
American Medical Association (AMA)
Liu, Weiming& Ling, Jiawen& Chen, Yiyi& Wu, Yan& Lu, Pei-Rong. The Association between Adiposity and the Risk of Glaucoma: A Meta-Analysis. Journal of Ophthalmology. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1185830
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1185830